Carolina Panthers at New Orleans Saints Predictions & Picks – Panthers Appealing Underdogs For Key NFL Clash
- Carolina tipped to cover +2.5 in spread
- New Orleans are 1-4 at home and 1-5 ATS in their last six games
- Betting underdog has covered in each of last three meetings
Carolina Panthers at New Orleans Saints Predictions & Picks
Carolina are tipped to cover as a betting underdog in this big NFC South clash.
The Panthers have lost three straight, but Bryce Young has been playing some good football and New Orleans have a terrible record at the Superdome this season.
- New Orleans Saints are 1-4 at home this season
- New Orleans Saints are 1-5-0 ATS in their last 6 games
- The betting underdog has covered in each of the last 3 meetings
- The Under cashed in both of last season’s meetings
Head To Head
- New Orleans Saints lead the all-time series 34-29
- New Orleans Saints won 20-17 when the two teams last met in December 2025
Carolina Panthers Form
Carolina go into this big NFC South showdown in desperate need of a win, having lost three straight to fall to 3-5.
The Panthers responded to a 59-37 defeat to Chicago on opening day with a 34-3 blowout of Atlanta on the road, but failed to follow that up as they lost 21-18 in Cleveland.
They bounced back to upset Detroit a week later, 32-26, and following that up with a 25-14 success in Philadelphia.
However, Carolina have not won since that success against the Eagles back on October 18.
The Panthers have sandwiched a 27-19 road defeat to Green Bay with home losses at the hands of Tampa Bay, 43-13, and Denver, 26-21.
New Orleans Saints Form
New Orleans enter this matchup having won at home for the first time this season, improving their record to 3-5.
The Saints lost 31-30 in overtime in Detroit in Week 1, but bounced back a week later as they travelled to Baltimore to upset the Ravens, 24-17.
They failed to build on that though, losing three straight at home as they were beaten 35-27 by Las Vegas, 45-24 by Atlanta, and 23-13 by Minnesota.
New Orleans finally stopped the rot with a 34-27 win at the New York Giants, only to then lose 16-10 to Pittsburgh in Paris.
The Saints did rebound at home though, finally notching their first Superdome success of 2026 as they beat Cleveland in overtime, 23-22.
Verdict
Carolina come into this matchup on a losing run, but they have shown promising signs in the losses to Denver and Green Bay.
New Orleans possess a miserable home record too, despite the win over Cleveland, so give us the Panthers and the free points.
New Orleans possess a miserable home record too, despite the win over Cleveland, so give us the Panthers and the free points.
Leigh Copson
Sports Editor • 25+ Years Experience, US & Combat Sports Specialist
US sports writer covering the NFL, NBA, NHL, boxing and MMA, with previews, predictions and betting tips across the major American leagues.
During his career at the Press Association and online sports sites including FreeTips and ExpertPicks.com, he has covered some of the biggest sporting events on the planet, including the Super Bowl, the Champions League Final and the World Cup Final.
He has also covered almost every major boxing match and UFC fight card during this time.. His specialist sports are American Football, Basketball, Ice Hockey, Boxing, Mixed Martial Arts and Football.