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San Francisco 49ers at Buffalo Bills Preview & Picks – Back Bills For 7th Straight NFL Win

leigh-copson
27 Nov 2024
leigh-copson
Leigh Copson 27 Nov 2024
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  • San Francisco 49ers at Buffalo Bills picks for Sunday, December 1
  • Game is taking place at Highmark Stadium
  • Preview, predictions, stats & form
(Getty Images)
    San Francisco 49ers at Buffalo Bills Preview & Picks
  • San Francisco 49ers at Buffalo Bills Preview & Picks
  • Head To Head
  • San Francisco 49ers Form
  • Buffalo Bills Form

San Francisco 49ers at Buffalo Bills Preview & Picks

Buffalo are tipped to cover as they win this Sunday Night Football matchup.

The Bills have built up a head of steam and not only have they been flawless at home this season, Josh Allen has done his best work at Highmark Stadium.

  • Buffalo Bills are on a 6-game win streak
  • Buffalo Bills are 5-1-0 ATS in their last 6 games
  • San Francisco 49ers are 1-4-0 ATS on the road this season
  • The Over has cashed in 5 of Buffalo’s previous 6 games

Head To Head

  • Buffalo Bills lead the all-time series 7-6
  • Buffalo Bills won 34-24 when the two teams last met in December 2020

San Francisco 49ers Form

San Francisco make the long road trip in desperate need of a victory, having lost back-to-back games to fall to 5-6.

The 49ers opened the season with a 32-19 win over the New York Jets, but they failed to follow that up as went on to lose four of their next six games.

That rough run included a couple of division losses to the Los Angeles Rams, 27-24, and Arizona, 24-32, while they did beat one NFC West rival, Seattle, 36-24.

San Francisco did manage back-to-back wins to end October and start November, beating Dallas 30-24 and Tampa Bay 23-20, but they have not won since.

The 49ers fell to a 20-17 defeat when they hosted Seattle, and that was followed by a 38-10 loss at Green Bay a week ago.

Buffalo Bills Form

Buffalo go into this game in red-hot form, having won six straight games to take their record to 9-2.

The Bills raced out of the blocks with three consecutive victories, only to then lose back-to-back road games, 35-10 in Baltimore and 23-20 at Houston.

They have not lost since that defeat to the Texans though, sparking this six-game winning run with a 23-20 victory at the New York Jets.

Buffalo then beat Tennessee at home, 34-10, before heading to Seattle to down the Seahawks 31-10.

The Bulls then sandwiched a 30-20 victory in Indianapolis with important home victories over Miami, 30-27, and Kansas City, 30-21.

Verdict

Buffalo are the team in form and quarterback Josh Allen is playing at an MVP level.

That spells trouble for a struggling San Francisco defense, so we expect the Bills to get the win and cover in this one.

Best Bet1: Buffalo -7.0 Spread @-111.11 at Stake.us - 4 Units
Best Bet2: Over 44.5 Total Points @-111.11 at Stake.us - 2 Units
Buffalo -7.0
Spread
@-111.11 - 4 Units
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Bet at Stake.us
Over 44.5
Total Points
@-111.11 - 2 Units
55 Stake Cash no deposit & 550,000 Gold Coins & 5% Rakeback
Use promo code NEWBONUS

Sign up with the code NEWBONUS. When you verify your account get 25 Stake Cash for free PLUS 250,000 Gold Coins and 5% Rakeback! No deposit required. Login each day for the next 30 days and get an additional 30 Stake Cash AND 300,000 Gold Coins. 21+ only. T&Cs apply. Excludes NY,NV,ID, KY,WA, MI.

Bet at Stake.us