Oregon at Ohio State Predictions & Picks – Buckeyes To Lean On Defense In College Football Win
- Ohio State tipped to cover -7.5 spread against Oregon
- Buckeyes' defense is expected to limit an Oregon team that has struggled on the road
- Ohio State have lost key offensive player Julian Sayin but remain strong at home
Oregon at Ohio State Predictions & Picks
Ohio State are tipped to cover as they return to winning ways on Saturday.
The Buckeyes’ offense has struggled without Julian Sayin, but they can lean on a talented defense against an Oregon team that has underwhelmed and not travelled well.
- Ohio State are 6-2 this season
- Oregon are 1-2 on the road this season
- Oregon are 3-5-0 ATS this season
- The Under has cashed in 3 of Ohio State’s last 4 games
Head To Head
- Ohio State lead the all-time series 10-2
- Ohio State won 41-21 when the two teams last met in January 2025
Oregon Form
Oregon head to Ohio State having rebounded from their third conference loss of the season to improve to 5-3.
The Ducks made hard work of their 34-27 season-opening win over Boise State, and then suffered a surprise 39-31 defeat at Oklahoma State as their stock plummeted.
They rebounded with an 84-0 shutout of Portland State, before opening their Big Ten campaign with a 41-27 victory at USC.
Oregon failed to make it three-in-a-row though, as they were beaten 21-15 at UCLA, and they were then unable to back up a 17-14 victory over Nebraska, as they lost 21-10 at Illinois.
The Ducks do make this trip on the back of a win though, having downed Northwestern last weekend, 34-26.
Ohio State Form
Ohio State go into this game looking to rebound from their second defeat of the season, which has left them 6-2.
The Buckeyes opened with three non-conference games, sandwiching a 24-23 defeat at Texas with blowout wins over Ball State, 56-3, and Kent State, 59-3.
They then kicked off their Big Ten schedule with a 41-19 win over Illinois, and backed that up by beating Iowa 31-14 on the road, and Maryland 45-16 at home.
That set up a huge matchup with defending national champions Indiana, and Ohio State overcame the loss of quarterback Julian Sayin as they ground out a 19-15 victory.
However, in their first full game without Sayin, the Buckeyes lost 30-18 at USC last weekend.
Verdict
Ohio State’s first outing without Sayin proved to be a rough one, but they are back home for this one and they do still boast a tough defense.
Therefore we are backing the Buckeyes to bounce back against an Oregon team that has disappointed this season.
Therefore we are backing the Buckeyes to bounce back against an Oregon team that has disappointed this season.
Leigh Copson
Sports Editor • 25+ Years Experience, US & Combat Sports Specialist
US sports writer covering the NFL, NBA, NHL, boxing and MMA, with previews, predictions and betting tips across the major American leagues.
During his career at the Press Association and online sports sites including FreeTips and ExpertPicks.com, he has covered some of the biggest sporting events on the planet, including the Super Bowl, the Champions League Final and the World Cup Final.
He has also covered almost every major boxing match and UFC fight card during this time.. His specialist sports are American Football, Basketball, Ice Hockey, Boxing, Mixed Martial Arts and Football.