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Home / MLB / Cleveland Guardians at Tampa Bay Rays Predictions & Picks – Guardians To Spring Another MLB Playoffs Upset

Cleveland Guardians at Tampa Bay Rays Predictions & Picks – Guardians To Spring Another MLB Playoffs Upset

  • Cleveland tipped to upset the Tampa Bay on the road for a second consecutive night
  • Parker Messick has a strong record; Rays' Freddy Peralta struggled with consistency
  • Cleveland enters with momentum, having won four straight games
Leigh Copson
By Leigh Copson • Sports Editor
25+ Years Experience, US & Combat Sports Specialist
Updated:
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mlb guardians rays game 2
Our Tip
Stake.com

Moneyline

Cleveland Win

Odds

110.00

Place Bet
Stake.com

Total Runs

Under 7.0

Odds

-125.00

Place Bet

Cleveland Guardians at Tampa Bay Rays Predictions & Picks

Cleveland are tipped to upset Tampa Bay on the road for the second night in a row.

Parker Messick was shaky in his last postseason start, but he has been excellent over the course of the season and did pitch well in his regular season meetings with the Rays.

His counterpart, Freddy Peralta, has ridden a rollercoaster of form this year and has been hittable.
  • Cleveland Guardians are 13-4 in their last 17 games
  • Cleveland Guardians are 7-2 in their last 9 road games
  • Cleveland’s Parker Messick is 12-9 with a 2.56 ERA
  • Tampa starter Freddy Peralta posted a 4.42 ERA this season
  • The Under has cashed in 7 of the last 9 meetings

Head To Head

  • Cleveland Guardians lead the all-time series 116-91
  • Cleveland Guardians lead this MLB playoff series 1-0
  • Cleveland Guardians won 7-2 when the two teams last met on October 12

Cleveland Guardians Form

Cleveland enter the second game of this series with plenty of momentum, having now won four straight games.

The Guardians made a slow start to the postseason as they lost back-to-back home games against Chicago, but they turned it around with three straight wins, and then made a winning start to this series with Tampa on Monday night.

DatePlayoff OppositionW/LScore
Oct-03 vs Chicago White Sox L 0-3
Oct-05 vs Chicago White Sox L 3-4
Oct-07 at Chicago White Sox W 9-3
Oct-08 at Chicago White Sox W 9-5
Oct-10 vs Chicago White Sox W 2-0
Oct-12 at Tampa Bay Rays W 7-3

Tampa Bay Rays Form

Tampa enter this matchup looking to rebound from their first defeat of the 2026 postseason.

The Rays made straightforward work of the New York Yankees, sweeping the team from the 'Big Apple' in three games, but they made a losing start to this series, falling 7-3 to Cleveland on Monday.

DatePlayoff OppositionW/LScore
Oct-03 vs New York Yankees W 1-0
Oct-05 vs New York Yankees W 5-2
Oct-07 at New York Yankees W 4-3
Oct-12 vs Cleveland Guardians L 3-7

Starting Pitchers

PlayerTeamRecordERAStrikeoutsInnings
Parker Messick Cleveland Guardians 12-9 2.56 193 186.1
Freddy Peralta Tampa Bay Rays 10-11 4.42 156 169.0

Verdict

Beating Tampa Bay on the road on back-to-back nights is a big ask, but Cleveland are capable of pulling it off.

Messick has done an excellent job against the Rays this season, while the bats can get after the hittable Peralta to ensure the Guardians return home with a 2-0 series lead.

Stake.com
Top Pick

Cleveland Win

at Stake.com

Stake.com

Under 7.0

at Stake.com

-125.00Visit Site
Leigh Copson
Leigh Copson

Sports Editor • 25+ Years Experience, US & Combat Sports Specialist

US sports writer covering the NFL, NBA, NHL, boxing and MMA, with previews, predictions and betting tips across the major American leagues.


During his career at the Press Association and online sports sites including FreeTips and ExpertPicks.com, he has covered some of the biggest sporting events on the planet, including the Super Bowl, the Champions League Final and the World Cup Final.

He has also covered almost every major boxing match and UFC fight card during this time.. His specialist sports are American Football, Basketball, Ice Hockey, Boxing, Mixed Martial Arts and Football.

Follow more of Leigh's work on Muckrack and connect with him on LinkedIn.

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