Home / College Football / Missouri at Ole Miss Predictions & Picks – Underdog Tigers To Register College Football Cover
Missouri at Ole Miss Predictions & Picks – Underdog Tigers To Register College Football Cover
- Missouri tipped to cover spread as underdogs versus Ole Miss
- Missouri’s strong defense and running game are highlighted as key advantages
- Recommendation is to back Missouri +6.5 and the Under 59.5 total points

Missouri at Ole Miss Predictions & Picks
Missouri are tipped to cover as a betting underdog in Mississippi.
The Tigers are a solid defensive unit, and they can also lean on the run game to chew up the clock and lessen the Rebels’ time with the football, resulting in a cover.
- Missouri are 2-0-0 ATS in their last 2 conference games
- Ole Miss are 2-3-0 ATS this season
- The Under has cashed in 3 of Missouri’s last 4 games
- The Under hit in both of Ole Miss’ previous 2 home games
Head To Head
- Missouri lead the all-time series 7-1
- Missouri won 38-27 when the two teams last met in October 2019
Missouri Form
Missouri go into this big SEC matchup looking to make it three wins in a row and improve their record to 6-1.
The Tigers opened the season with three straight non-conference games, and came out on top in all three of them.
They blew out Arkansas-Pine Bluff 54-14, and backed that up by beating Kansas 38-21 and Troy 27-17.
Missouri failed to make it four-in-a-row in their conference opener, losing 31-24 at Mississippi State, but their response has been nothing short of impressive.
The Tigers bounced back with a stunning 45-17 demolition of a top-10 Florida team, before holding Texas A&M to just six points in a 27-6 victory.
Ole Miss Form
Ole Miss enter this matchup having rebounded from their first loss of the season with a victory that took them to 4-1.
The Rebels kicked off the campaign with back-to-back non-conference wins, beating Louisville 41-38 and Charlotte 41-9.
That set them up for a huge SEC opener against LSU and Lane Kiffin, and they got the better of their former head coach thanks to a 32-24 victory.
Ole Miss were brought back down to Earth a week later by a 52-28 defeat at Florida, but they rebounded in emphatic fashion.
The Rebels pounced on a sloppy and ill-disciplined Vanderbilt team to record a 52-17 victory last weekend.
Verdict
Ole Miss bounced back strongly from the loss to Florida, and they are rightly favorites at home.
However, it is tough to ignore how good Missouri have been in recent weeks, and they have enough about them to cover the spread as an underdog.
However, it is tough to ignore how good Missouri have been in recent weeks, and they have enough about them to cover the spread as an underdog.
Leigh Copson
Sports Editor • 25+ Years Experience, US & Combat Sports Specialist
US sports writer covering the NFL, NBA, NHL, boxing and MMA, with previews, predictions and betting tips across the major American leagues.
During his career at the Press Association and online sports sites including FreeTips and ExpertPicks.com, he has covered some of the biggest sporting events on the planet, including the Super Bowl, the Champions League Final and the World Cup Final.
He has also covered almost every major boxing match and UFC fight card during this time.. His specialist sports are American Football, Basketball, Ice Hockey, Boxing, Mixed Martial Arts and Football.