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USC at Indiana Predictions & Picks – Hoosiers’ Cover Struggles To Continue In College Football
- USC tipped to cover as underdogs against Indiana
- Indiana are 1-8-0 ATS this season, struggling to cover spreads
- USC have covered in two of their last three games

USC at Indiana Predictions & Picks
USC are tipped to cover as a betting underdog in this important Big Ten clash.
Indiana continue to pick up wins, but with the offense struggling they have rarely covered the number this year, and they have won just one of their last six games by double digits.
- Indiana are 1-8-0 ATS this season
- USC are 2-1-0 ATS in their previous 3 games
- The Under has cashed in each of USC’s last 4 games
- The Under has hit in each of Indiana’s last 4 games
Head To Head
- USC lead the all-time series 4-0
- USC won 28-7 when the two teams last met in September 1982
USC Form
USC head to Indiana on the back of a victory over Ohio State that took them to 7-2 and kept them in the Big Ten race.
The Trojans opened the season with three non-conference wins, beating San Jose State 42-26, Fresno State 39-0 and Louisiana 49-30.
They then kicked off their Big Ten slate with a 42-35 win at Rutgers, only to suffer an early setback as they were beaten 41-27 in Oregon.
USC rebounded by beating Washington 25-21 at home and Penn State 31-23 on the road, but failed to make it three-in-a-row as they were beaten 24-7 in Wisconsin.
The Trojans did offer an immediate response though, as they took down Ohio State at home, 30-18.
Indiana Form
Indiana come into this matchup having rebounded from their first defeat since 2024 with back-to-back wins to reach 8-1.
The Hoosiers began their defence of the national crown with three non-conference victories, beating North Texas 52-16, Howard 55-0 and Western Kentucky 38-0.
They then kicked off their Big Ten schedule with three more victories, edging Northwestern at home, 29-23, before beating Rutgers and Nebraska on the road, 47-15 and 20-17 respectively.
Indiana’s run was finally brought to an end by a 19-15 home defeat to Ohio State, but they have bounced back over the past couple of weeks.
The Hoosiers beat Michigan 13-6 on the road, before returning home to see off Minnesota, 23-16.
Verdict
Indiana are winning games, but the offense is struggling and they are making hard work of it.
As a result they have covered just once this season, so give us the visiting Trojans and the free points in this Big Ten showdown.
As a result they have covered just once this season, so give us the visiting Trojans and the free points in this Big Ten showdown.
Leigh Copson
Sports Editor • 25+ Years Experience, US & Combat Sports Specialist
US sports writer covering the NFL, NBA, NHL, boxing and MMA, with previews, predictions and betting tips across the major American leagues.
During his career at the Press Association and online sports sites including FreeTips and ExpertPicks.com, he has covered some of the biggest sporting events on the planet, including the Super Bowl, the Champions League Final and the World Cup Final.
He has also covered almost every major boxing match and UFC fight card during this time.. His specialist sports are American Football, Basketball, Ice Hockey, Boxing, Mixed Martial Arts and Football.