menu
    Select your language
    • English
    Betting
timer

This event has expired. Please see other tips here

New Orleans Saints at San Francisco 49ers Preview & Picks – In-Form 49ers To Cover In NFL Win

leigh-copson
By Leigh Copson
23 Nov 2022
Share
leigh-copson
Leigh Copson 23 Nov 2022
Share this article
Or copy link
Copy
  • New Orleans Saints at San Francisco 49ers picks for Sunday, November 27
  • Matchup gets underway at 16:25 ET at Levi’s Stadium
  • Preview, stats & head-to-head
New Orleans Saints at San Francisco 49ers NFL Preview & Picks
    New Orleans Saints at San Francisco 49ers Preview & Picks
  • New Orleans Saints at San Francisco 49ers Preview & Picks
  • Head To Head
  • New Orleans Saints Form
  • San Francisco 49ers Form
  • New Orleans Saints at San Francisco 49ers FAQs

New Orleans Saints at San Francisco 49ers Preview & Picks

San Francisco are tipped to cover in a home win.

The 49ers offense is firing and the defense has been shutting down opposition offenses recently.

They now face a hit-and-miss New Orleans team who are yet to cover on the road this season.

  • San Francisco are 6-2-0 ATS in their last 8 home games
  • San Francisco are 10-2-0 ATS in their last 12 games vs NFC teams
  • New Orleans Saints are 0-4-0 ATS on the road this season
  • The Over has cashed in 4 of San Francisco’s last 6 games
  • The Over has hit in 5 of San Francisco’s last 8 games

Head To Head

  • San Francisco 49ers lead the all-time series 49-27-2
  • New Orleans Saints won 27-13 when the teams last met in November 2020

New Orleans Saints Form

New Orleans go into this game with a 4-7 record but still in the hunt in the wide open NFC South.

The Saints opened the season with a 27-26 win in Atlanta, only to see their form quickly tail off.

They lost 20-10 at home to Tampa Bay and 22-14 in Carolina, before heading to London for a 28-25 defeat to Minnesota.

New Orleans stopped the rot with a 39-32 upset of Seattle, but immediately returned to losing ways with a 30-26 defeat to Cincinnati and a 42-34 loss in Arizona.

A 24-0 shutout win against Las Vegas did not kick-start their season either, as they then lost 27-13 to Baltimore and 20-10 in Pittsburgh.

The Saints to go into this game on the back of a victory though, having beaten the Los Angeles Rams 27-20 last weekend.

San Francisco 49ers Form

San Francisco return home looking to extend a three-game win streak after Monday’s win in Mexico.

The 49ers went 1-1 through the first two games as they bounced back from a shock 19-10 defeat in Chicago with a 27-7 win against Seattle.

They tripped up again a week later with a 11-10 defeat in Denver, but responded to that with a couple of wins.

San Francisco downed the Los Angeles Rams 24-9 and Carolina 37-15, only to then lose their next two games to fall back below .500.

The Niners suffered a surprise 28-14 defeat in Atlanta before losing 44-23 at home to Kansas City, but they at least stopped the rot before the bye week with a 31-14 win at the Rams.

They have built on that win since the bye, backing up a 22-16 win at home to the Los Angeles Chargers with a 38-10 win against the Cardinals in Mexico.

New Orleans Saints at San Francisco 49ers FAQs

Where can I watch the New Orleans Saints at San Francisco 49ers live stream?

You can watch the New Orleans Saints at San Francisco 49ers live stream at Stake.

What is the New Orleans Saints at San Francisco 49ers start time?

The New Orleans Saints at San Francisco 49ers game is set to start at 16:25 ET.

Verdict

San Francisco are the team in better form and are delivering on both sides of the football.

They are backed to extend their win streak and cover at the expense of the ‘travel sick’ Saints.

Best Bet: San Francisco -9.5 Spread @-111.11 at Stake.com - 4 Units
Value Bet: Over 43.0 Total Points @-111.11 at Stake.com - 2 Units
San Francisco -9.5
Spread
@-111.11 - 4 Units
25 SC no deposit & 250,000 GC
Use promo code NEWBONUS

Get 25 Stake Cash & 250,000 Gold Coins when you sign up with code NEWBONUS at Stake.us. USA only. Excludes certain States including NY,NV,ID, KY,WA. 18+ only. Terms and Conditions apply.

Bet at Stake.com
Over 43.0
Total Points
@-111.11 - 2 Units
25 SC no deposit & 250,000 GC
Use promo code NEWBONUS

Get 25 Stake Cash & 250,000 Gold Coins when you sign up with code NEWBONUS at Stake.us. USA only. Excludes certain States including NY,NV,ID, KY,WA. 18+ only. Terms and Conditions apply.

Bet at Stake.com

See also

Sports Events Starts in

Latest News

See all

Latest news

news image
Wildcats Cover

Central Michigan vs Northwestern Preview & Picks – Back Wildcats In GameAbove Sports Bowl

College Football
12 Dec 2025
news image
Low-Scoring Game

Clemson vs Penn State Preview & Picks – Under To Cash In Pinstripe Bowl

College Football
15 Dec 2025
news image
BYU Cover

BYU vs Georgia Tech Preview & Picks – Cougars To Cover In Pop-Tarts Bowl Win

College Football
12 Dec 2025
news image
Texans Cover

Houston Texans at Los Angeles Chargers Preview & Picks - Take Texans & Free Points In NFL Clash

NFL
25 Dec 2025
news image
Back Mizzou

Missouri vs Virginia Preview & Picks – Tigers To Cover 1-Touchdown Spread In Gator Bowl

College Football
17 Dec 2025
news image
Packers Win

Baltimore Ravens at Green Bay Packers Preview & Picks - Back Packers To Bounce Back In NFL

NFL
25 Dec 2025
news image
Houston Win

LSU vs Houston Preview & Picks – Cougars To Tame Tigers In Texas Bowl

College Football
12 Dec 2025
news image
Niners Cover

Chicago Bears at San Francisco 49ers Preview & Picks - 49ers To Win Potential NFL Playoff Preview

NFL
25 Dec 2025
Load More
  • 18 Logo
  • Game Care Logo
 bonus image
Copyright © 2025 Reproduction in whole or in part in any form or medium without express written permission is prohibited. Players must be 18 or over and located in jurisdictions where online gambling is legal. Please play responsibly. Bet with your head, not over it. If you or someone you know has a gambling problem, and wants help, call or visit: Gamcare . #Ads © 2025 expertpicks.com