Get Free Alerts

Never miss a tip. Choose your sports and get instant updates.

Football

Football

8 active tips

Basketball

Basketball

1 active tip

Cricket

Cricket

1 active tip

Tennis

Tennis

1 active tip

Esports

Esports

1 active tip

Free forever. No spam. Unsubscribe anytime by leaving the channel.

Top offers

Home / MLB / Detroit Tigers at Chicago White Sox Predictions & Picks – Over To Cash In Windy City MLB Clash

Detroit Tigers at Chicago White Sox Predictions & Picks – Over To Cash In Windy City MLB Clash

Quick Read

  • Both starting pitchers have high ERAs and are vulnerable to runs
  • Tigers struggle on the road; lean towards White Sox victory
  • Best bet is Over 8.5 total runs scored in the game
Leigh Copson
Written by Leigh Copson
Sports Editor25+ Years Experience, US & Combat Sports Specialist
Updated: Sep 18, 2026
Detroit Tigers at Chicago White Sox Predictions & Picks – Over To Cash In Windy City MLB Clash
Our TipStrong confidence
Stake.us

Total Runs

Over 8.5

Odds

-111.11

Place Bet
Stake.us

Moneyline

Chicago Win

Odds

-138.89

Place Bet

Detroit Tigers at Chicago White Sox Predictions & Picks

The Over is tipped to cash in the second game of this series.

Both pitchers have proven to be very hittable in their limited action this season, so the runs could pile up in this one.

  • Detroit Tigers are 4-12 in their last 16 road games
  • Detroit starter Andrew Sears is 0-1 with a 5.40 ERA
  • Chicago pitcher David Sandlin is 2-2 with a 5.64 ERA

Head To Head

  • Detroit Tigers lead the all-time series 1149-1121-15
  • Chicago White Sox won 3-1 when the two teams last met on September 17

Detroit Tigers Form

Detroit enter the second game of this series having won seven of their last 10 games, but having lost their last two.

DateOppositionW/LScore
Sep-07 vs Minnesota Twins W 5-4
Sep-08 vs Minnesota Twins L 2-3
Sep-09 vs Minnesota Twins W 7-2
Sep-11 vs Colorado Rockies W 6-2
Sep-12 vs Colorado Rockies W 11-7
Sep-13 vs Colorado Rockies W 8-1
Sep-14 at Toronto Blue Jays W 6-5
Sep-15 at Toronto Blue Jays W 10-1
Sep-16 at Toronto Blue Jays L 1-5
Sep-17 at Chicago White Sox L 1-3

Chicago White Sox Form

Chicago go into this matchup having snapped a two-game losing sequence last night, but having lost seven of their previous 10 games.

DateOppositionW/LScore
Sep-08 vs Pittsburgh Pirates L 3-9
Sep-09 vs Pittsburgh Pirates L 2-4
Sep-10 vs Pittsburgh Pirates L 0-2
Sep-11 at St Louis Cardinals L 3-7
Sep-12 at St Louis Cardinals W 6-5
Sep-13 at St Louis Cardinals L 1-3
Sep-14 at Cleveland Guardians W 7-3
Sep-15 at Cleveland Guardians L 6-7 W/O
Sep-16 at Cleveland Guardians L 3-6
Sep-17 vs Detroit Tigers W 3-1

Starting Pitchers

PlayerTeamRecordERAStrikeoutsInnings
Andrew Sears Detroit Tigers 0-1 5.40 13 16.2
David Sandlin Chicago White Sox 2-2 5.6429 30.1

Verdict

Detroit’s recent struggles on the road continued, so we are leaning towards the White Sox in this one.

However, the more appealing bet is the Over – these two pitchers have been lit up several times in their limited innings.

Stake.us
Top Pick

Over 8.5

at Stake.us

-111.11Visit Site
Stake.us

Chicago Win

at Stake.us

-138.89Visit Site
Leigh Copson
Leigh Copson

Sports Editor25+ Years Experience, US & Combat Sports Specialist

During his career he has covered some of the biggest sporting events on the planet, including the Super Bowl, the Champions League Final and the World Cup Final. He has also covered almost every major boxing match and UFC fight card during this time.. His specialist sports are American Football, Basketball, Ice Hockey, Boxing, Mixed Martial Arts and Football.


Follow more of Leigh's work on Muckrack.

Read More