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Home / NFL / Green Bay Packers at San Francisco 49ers Picks & Betting Tips – Packers To Cover

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Green Bay Packers at San Francisco 49ers Picks & Betting Tips – Packers To Cover

Quick Read

  • Green Bay Packers at San Francisco 49ers tips for Sunday, September 26
  • Matchup gets underway at 20:20 ET at Levi’s Stadium
  • Preview, stats & head-to-head
Leigh Copson
Written by Leigh Copson
Sports Editor • 25+ Years Experience, US & Combat Sports Specialist
Updated:
nfl green bay packers san francisco 49ers

Green Bay Packers at San Francisco 49ers Picks & Betting Tips


Green Bay could cover at Levi’s Stadium for the second season running.

The 49ers’ offense is built around the run game but their running back room is hit with injuries.

And last weekend Aaron Rodgers looked more like his old self as Green Bay rebounded from a nightmare opening day.

The Packers’ Monday night showing gives me confidence to back them with the points in what could be a close game.

  • San Francisco 49ers have a 2-0 record 
  • San Francisco 49ers are 1-1-0 ATS so far this season
  • San Francisco 49ers have injury problems at running back
  • Green Bay Packers have a 1-1 record
  • Green Bay Packers are 1-1-0 ATS so far this season
  • Green Bay Packers are 23-15-0 ATS under Matt LaFleur
  • Green Bay Packers are 10-7-0 ATS as the road team under Matt LaFleur

Head To Head


  • Green Bay Packers lead the all-time series 37-32-1
  • Green Bay Packers won 34-17 at Levi’s Stadium last season

Green Bay Packers Form


Green Bay made a shocking start to the season as they were blown out 38-3 by New Orleans in Jacksonville.

Aaron Rodgers threw two picks and Jordan Love fumbled as the Packers were embarrassed.

They responded in emphatic fashion in Week 2 though, crushing Detroit in Monday Night Football.

Rodgers threw four TDs and Aaron Jones found the endzone four times as the Packers ran away with it.

QB Rodgers has completed 37 of his 55 pass attempts this season for 388 yards, four TDs and two picks.

WR Davante Adams has been Rodgers’ favorite target, hauling in 13 of his 16 targets for 177 yards.

RB Aaron Jones has 137 all-purpose yards and four touchdowns after his impressive display against Detroit.

Green Bay Packers Injury Report


  • TE Dominique Dafney (hip) - Questionable
  • G Elgton Jenkins (ankle) - Doubtful

San Francisco 49ers Form


San Francisco have a perfect 2-0 record but their performances have been far from perfect so far.

The 49ers beat Detroit 41-33 on opening weekend but almost blew a huge lead in the final two minutes.

They then managed just one score through three quarters in Philadelphia before finally sealing a 17-11 win with a Jimmy Garoppolo TD run and Robbie Gould field goal.

Garoppolo remains starting QB ahead of rookie Trey Lance. ‘Jimmy G’ is 39/55 for 503 yards and two touchdowns.

Elijah Mitchell leads in rushing with 146 yards and a score, but he is out and both Jamycal Hasty and Trey Sermon are questionable.

WR Deebo Samuel is a weapon that should be available though. Through two games he has 282 receiving yards and a TD.

San Francisco 49ers Injury Report


  • RB JaMycal Hasty (ankle) - Out
  • DT Kevin Givens (ankle) - Out
  • RB Elijah Mitchell (shoulder) - Doubtful
  • DE Arik Armstead (adductor) - Questionable
  • DT Javon Kinlaw (knee) - Questionable
  • CB Emmanuel Moseley (knee) - Questionable

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Leigh Copson
Leigh Copson

Sports Editor • 25+ Years Experience, US & Combat Sports Specialist

Leigh Copson is the editor of expert picks and provides daily picks for the NFL, NBA, NHL, MLB boxing and MMA. He provides analysis of the big events across major American leagues every day.


He started out with the Press Association before moving online and working for ExpertPicks.com, FreeTips.com and other sports news and betting sites. 

He has covered some of the biggest sporting events on the planet, including the Super Bowl, the Champions League Final and the World Cup Final and has covered almost every major boxing match and UFC fight card during this time.

Follow more of Leigh's work on Muckrack and connect with him on LinkedIn.


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