Indianapolis Colts at Pittsburgh Steelers Preview & Picks – Colts’ Stampede To Continue In NFL
28 Oct 2025
Read More
Seattle Seahawks at San Francisco 49ers Picks & Betting Tips – Seahawks To Stop Losing Skid
- Seattle Seahawks at San Francisco 49ers tips for Sunday, October 3
- Matchup gets underway at 16:05 ET at Levi’s Stadium
- Preview, stats & head-to-head
- Seattle Seahawks at San Francisco 49ers Picks & Betting Tips
- Head To Head
- Seattle Seahawks Form
- Seattle Seahawks Injury Report
- San Francisco 49ers Form
- San Francisco 49ers Injury Report
- Seattle Seahawks at San Francisco 49ers FAQs
Seattle Seahawks at San Francisco 49ers Picks & Betting Tips
Seattle Seahawks at San Francisco 49ers Picks & Betting Tips
Russell Wilson has never lost three straight. He can prevent that from happening on Sunday.
San Francisco are being ravaged by injuries, especially in their secondary and that is what Wilson will target.
Wilson can link up with DK Metcalf and Tyler Lockett for some big plays as the Seahawks win.
- Seattle Seahawks swept San Francisco 49ers last season
- Seattle Seahawks have won 6 of their last 7 at San Francisco 49ers
- Seattle Seahawks are 15-5 ATS in the last 20 meetings
- San Francisco 49ers are dealing with a bunch of injuries
Head To Head
- Seattle Seahawks lead the all-time series 28-17
- Seattle Seahawks beat San Francisco 49ers twice last season
Seattle Seahawks Form
Seattle are trying to avoid a third consecutive defeat this weekend.
The Seahawks opened with a 28-16 win over Indianapolis but it has been all downhill since then.
They blew a 14-point lead in the fourth quarter as they lost at home to Tennessee in overtime, 33-30.
That was followed up by a 30-17 defeat at Minnesota that saw them fail to score a single point in the last 41 minutes of the game.
Despite Seattle’s underwhelming 1-2 record QB Russell Wilson has started the season in good form.
Wilson has gone 63/86 for 895 yards, seven touchdowns and no interceptions.
Tyler Lockett and DK Metcalf have been his favorite targets. Lockett has 309 yards and three scores off 16 catches, while Metcalf has turned 16 receptions into 220 yards and two scores.
In the backfield Chris Carson has 230 yards from scrimmage and three rushing touchdowns.
Defensively they have struggled. The Seahawks are giving up a league-worst 440.3 yards per game and rank #31 in total yards allowed.
In terms of points they are #21 in points allowed per game (26.3) and total points allowed (79).
Seattle Seahawks Injury Report
- WR Tyler Lockett (hip) - Questionable
- WR D'Wayne Eskridge (concussion) - Doubtful
- LB Benson Mayowa (neck) - Questionable
- RB Rashaad Penny (calf) - Out
- DE Alton Robinson (knee) - Questionable
- T Brandon Shell (ankle) - Out
San Francisco 49ers Form
San Francisco are looking to bounce back from losing their home opener in heart-breaking fashion.
The 49ers opened their season with a 41-33 win in Detroit that saw them dominate for 58 minutes before getting a little too careless in garbage time.
A 17-11 win over Philadelphia followed, but their perfect start came to an end with a 30-28 loss to Green Bay.
A Kyle Juszczyk touchdown reception with 37 seconds to go looked to have won it for the Niners, but the Packers marched into field goal range and Mason Crosby hit a 51-yarder as time expired.
Jimmy Garoppolo remains the starting QB ahead of rookie Trey Lance. He is 64/95 for four touchdowns and a pick.
Elijah Mitchell leads the team in rushing (146 yards, one TD), but he is dealing with an injury.
The biggest weapon the Niners have is WR Deebo Samuel. He already has 334 yards and a TD through three games.
TE George Kittle has caught 15 of his 18 targets for 187 yards but he is yet to find the endzone.
The defense is average in most statistical departments as they struggle with life post-Robert Saleh.
San Francisco 49ers Injury Report
- CB Josh Norman (chest) - Doubtful
- CB K'Waun Williams (calf) - Out
- RB Eli Mitchell (shoulder) - Questionable
- DT Javon Kinlaw (knee) - Questionable
- TE George Kittle (calf) - Questionable
Seattle Seahawks at San Francisco 49ers FAQs
Where can I watch the Seattle Seahawks at San Francisco 49ers live stream?
Check our live streaming calendar to see where to watch the Seattle Seahawks at San Francisco 49ers live stream.
Verdict
San Francisco have the better record but Seattle are in better physical shape coming into this.
Russell Wilson could light up an injury-hit 49ers secondary as the Seahawks avoid a third straight loss.
Russell Wilson could light up an injury-hit 49ers secondary as the Seahawks avoid a third straight loss.
Seattle +3.0
Spread
@-116.28 - 2 Units
55 Stake Cash no deposit & 550,000 Gold Coins & 5% Rakeback
Use promo code NEWBONUS
Sign up with the code NEWBONUS. When you verify your account get 25 Stake Cash for free PLUS 250,000 Gold Coins and 5% Rakeback! No deposit required. Login each day for the next 30 days and get an additional 30 Stake Cash AND 300,000 Gold Coins. 21+ only. T&Cs apply. Excludes WA, NY, NV, ID, KY, MI, VT, NJ, DE, WV, PA, RI & MD.
Seattle Seahawks
Moneyline
@130.00 - 1 Unit
25,000 Gold Coins + 1 Shuffle Cash
with referral code MAXBONUS
Join Shuffle.us using the referral code MAXBONUS and claim 25,000 Gold Coins + 1 Shuffle Cash to use at this leading crypto operator. No purchase is necessary to play. Promotions are void where prohibited by law. Shuffle.us is a play-for-fun website intended for amusement purposes only. Shuffle.us does not offer “real-money gambling.” Shuffle.us is a Social Gaming Platform and is only open to Eligible Participants, who are at least eighteen (18) years old or the age of majority in their jurisdiction (whichever occurs later) at the time of entry. Shuffle.us is committed to responsible social play, for more information visit gamingaddictsanonymous.org. Please read their Privacy Policy for more information. 21+.
- Select All
- American Football Events
- Baseball Events
- Basketball Events
- Boxing Events
- Esports Events
- Formula 1 Events
- Golf Events
- Horse Racing Events
- Ice Hockey Events
- NFL Events
- Olympics Events
- Politics Events
- Soccer Events
- UFC Events
Sports Events
Starts in
- COL Avalanche @ VGS Golden Knights
- BOS Celtics @ NY Knicks
- NY Knicks @ CHI Bulls
- LA Dodgers @ TOR Blue Jays - Game 6
- Penn State @ Ohio State
- Vanderbilt @ Texas
- WIN Blue Bombers @ MON Alouettes
- Indiana @ Maryland
- Georgia @ Florida
- CAL Stampeders @ BC Lions
- South Carolina @ Ole Miss
- Georgia Tech @ NC State
Latest News
-
Indy Cover -
Detroit CoverMinnesota Vikings at Detroit Lions Preview & Picks – Lions To Down Division Rivals In NFL28 Oct 2025 Read More
-
Buffalo CoverKansas City Chiefs at Buffalo Bills Preview & Picks – Takes Bills & Free Points In Huge NFL Showdown28 Oct 2025 Read More
-
Jaguars WinJacksonville Jaguars at Las Vegas Raiders Preview & Picks – Jags To Leave Las Vegas With NFL Victory28 Oct 2025 Read More
-
Visitors WinSeattle Seahawks at Washington Commanders Preview & Picks – Seahawks To Enjoy Sunday Night NFL Success29 Oct 2025 Read More
