Indianapolis Colts at Pittsburgh Steelers Preview & Picks – Colts’ Stampede To Continue In NFL
                                28 Oct 2025
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                            Cincinnati Bengals at San Francisco 49ers Preview & Picks – 49ers To Snap Losing NFL Run
- Cincinnati Bengals at San Francisco 49ers picks for Sunday, October 29
- Matchup gets underway at 16:25 ET at Levi’s Stadium
- Preview, predictions, stats & form
- Cincinnati Bengals at San Francisco 49ers Preview & Picks
- Head To Head
- Cincinnati Bengals Form
- San Francisco 49ers Form
Cincinnati Bengals at San Francisco 49ers Preview & Picks
Cincinnati Bengals at San Francisco 49ers Preview & Picks
San Francisco are tipped to cover as they return to winning ways.
The 49ers are dealing with some injuries, but they are back at home where they do their best work.
The defense is likely to set a low target that the Niners can meet in order to both win and cover.
- San Francisco 49ers are 10-0-0 ATS in their last 10 home games
- San Francisco 49ers are 4-1-0 ATS in their last 5 games against Cincinnati
- The 2 teams are allowing a combined 36.8 points per game
- The Under has hit in 4 of Cincinnati’s 6 games this season
Head To Head
- San Francisco 49ers lead the all-time series 13-4
- San Francisco 49ers won 26-23 when the two teams last met in December 2021
Cincinnati Bengals Form
Cincinnati return from the bye week looking to continue some improved form that has taken them to 3-3.
The Bengals opened the season with 24-3 defeat at division rivals Cleveland, and then lost 27-24 in their home opener against another AFC North opponent, Baltimore.
They finally got off the mark with a 19-16 win at home to the Los Angeles Rams in Week 3, but they did not immediately back that up.
Cincinnati went back out on the road a week later and produced a terrible offensive display as they were beaten 27-3 in Tennessee.
The Bengals have not lost since though, following up a 34-20 win in Arizona with a 17-13 home win against Seattle.
San Francisco 49ers Form
San Francisco return home looking to get back on track after consecutive defeats saw them fall to 5-2.
The 49ers opened the season with back-to-back road wins, beating Pittsburgh 30-7 and the Los Angeles Rams 30-23.
They then downed the New York Giants, 30-12 in their home opener and the first of three straight games at Levi’s Stadium.
The wins kept coming for San Francisco as they beat division rivals Arizona, 35-16, before blowing out long-time rivals Dallas, 42-10.
The 49ers’ streak came to an end when they went back out on the road though, as they lost 19-17 in Cleveland and 22-17 at Minnesota.
Verdict
San Francisco return home on the back of a couple of bad losses and with injuries mounting.
The 49ers’ have a tremendous recent record at Levi’s Stadium though, so we are backing them to stop the rot on Sunday.
                                        
                                                
                                                
                                            
                        The 49ers’ have a tremendous recent record at Levi’s Stadium though, so we are backing them to stop the rot on Sunday.
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                                            Sign up with the code NEWBONUS. When you verify your account get 25 Stake Cash for free PLUS 250,000 Gold Coins and 5% Rakeback! No deposit required. Login each day for the next 30 days and get an additional 30 Stake Cash AND 300,000 Gold Coins. 21+ only. T&Cs apply. Excludes WA, NY, NV, ID, KY, MI, VT, NJ, DE, WV, PA, RI & MD.
See also
- Las Vegas Raiders at Detroit Lions Preview & Picks – Lions To Cover In NFL Monday Night Win
- Los Angeles Rams at Dallas Cowboys Preview & Picks – Cowboys To Cover In NFL Victory
- Chicago Bears at Los Angeles Chargers Preview & Picks – Bears To Cover As Sunday NFL Underdog
- Tampa Bay Buccaneers at Buffalo Bills Preview & Picks – Bills Rebound From Shock NFL Loss
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