Detroit Lions at Buffalo Bills Predictions & Picks
Buffalo are tipped to cover the spread as they win their first proper outing at their new home.
Josh Allen was dealing in Week 1, and that spells big trouble for a Lions team that saw its secondary get gashed by the Saints as they a blew big lead before rallying in overtime.
- Buffalo Bills are 1-0-0 ATS this season
- Detroit Lions are 0-1-0 ATS after their 1st game
- The Over cashed in Buffalo’s victory in Houston
- The Over hit in Detroit’s win over New Orleans
Head To Head
- Buffalo Bills lead the all-time series 8-4-1
- Buffalo Bills won 48-42 when the two teams last met in December 2024
Detroit Lions Form
Detroit head to Buffalo with a 1-0 record, having rallied from blowing a massive lead to beat New Orleans 31-30 in overtime.
The Lions held a 21-point lead with less than five minutes remaining in the third quarter, only to give up two scores before the end of that period to let the Saints back into the game.
The hosts were then outscored 10-3 in the fourth, leaving the game locked at 24-24 at the end of regulation.
Amon-Ra St Brown put Detroit back in front in overtime, and they were able to close out the victory when the Saints failed to convert a two-point attempt after Noah Fant’s score.
Lions quarterback Jared Goff went 26/39 for 206 yards and two touchdowns, while Jahmyr Gibbs racked up 156 yards and two touchdowns on the ground.
Buffalo Bills Form
Buffalo go into their first regular season game at their new home stadium having made a successful start to the season on the road.
The Bills kicked things off with a trip to face a talented Houston team, and came away with a 36-31 victory.
The two teams went back and forth before Josh Allen finally settled matters with 196 seconds left on the clock, hitting Josh Palmer for the game-winning 34-yard score.
Allen finished the game 20/29 for 334 yards and two touchdowns, as he threw the football to seven different players.
Dalton Kincaid led the way in receiving yards, putting up 130, while new wide receiver DJ Moore marked his debut with 100 yards and a score.