Los Angeles head into this playoff matchup having closed out the regular season with three straight wins to finish 11-6.
The Chargers split their first six games of the season, but found some form in late October as they kicked off a four-game win streak with a 26-8 victory over New Orleans.
That run was halted by a 30-23 defeat to Baltimore, and although they rebounded to beat Atlanta 17-13, their form cooled off again.
Los Angeles lost back-to-back games to playoff-bound teams, Kansas City and Tampa Bay, but avoided a third straight loss as they beat Denver at home, 34-27.
The Chargers then backed up that victory on the road, beating to New England 40-7 and Las Vegas 34-20 to book their trip to the postseason.