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Home / College Football / North Carolina at Clemson Predictions & Picks – Take Tar Heels & Free Points In College Football

North Carolina at Clemson Predictions & Picks – Take Tar Heels & Free Points In College Football

Quick Read

  • UNC favored to cover as underdog vs Clemson
  • Both teams' offenses have struggled, strong defenses on show
  • Best bets: North Carolina +3.5, Under 43.5 points
Leigh Copson
Written by Leigh Copson
Sports Editor25+ Years Experience, US & Combat Sports Specialist
Updated: Sep 16, 2026
ncaaf north carolina clemson
Our TipStrong confidence
Stake.us

Spread

North Carolina +3.5

Odds

-111.11

Place Bet
Stake.us

Total Points

Under 43.5

Odds

-111.11

Place Bet

North Carolina at Clemson Predictions & Picks

North Carolina are tipped to cover as a betting underdog in this ACC clash.

Clemson have been their own worst enemy through the first two games, and it is tough to see the offense having much – if any – success against a dominant Tar Heels defense.

  • North Carolina are 2-0 this season
  • North Carolina are 1-0-0 ATS as a betting underdog
  • Clemson are 0-2-0 ATS after their first two games
  • The Under has cashed in 3 of the 4 games involving either team so far

Head To Head

  • Clemson lead the all-time series 41-19-1
  • Clemson won 38-10 when the two teams last met in October 2025

North Carolina Form

North Carolina head back out on the road with an unbeaten record, having won back-to-back non-conference games.

The Tar Heels kicked off the campaign with a trip to Ireland to face a TCU team that wrecked Bill Belichick’s debut last year, and they got a measure of revenge for that loss.

In a game dominated by defense, UNC scored 12 unanswered points to erase an early deficit and claim a 15-10 win.

North Carolina’s second win was more convincing, albeit the 35-3 victory came against weaker opposition in East Tennessee State.

Quarterback Billy Edwards went 15/20 for 244 yards and two touchdowns, with Jelani Thurman his leading receiver with 71 yards and a touchdown.

Clemson Form

Clemson go into their first conference game of the season looking to build on last week’s win in their home opener.

The Tigers made a miserable start to the season as they were blown out by LSU, 51-10, in primetime.

They rebounded from that loss at the first attempt, but it was still an underwhelming performance as they saw off Georgia Southern, 22-7.

Clemson took a 16-7 lead into half-time, and added just two more field goals after the restart to wrap up the victory.

Tait Reynolds, who replaced an injured Christopher Vizzina, went 16/27 for 178 yards, while wide receiver TJ Moore led the team with 103 yards and a score off seven grabs.

Verdict

Our Verdict
With both offenses spluttering at this time, this matchup will almost certainly be a defensive struggle.

For that reason we are taking the Tar Heels and the free points – it is tough to see Clemson hanging too many points on this tough UNC defense.

Stake.us
Top Pick

North Carolina +3.5

at Stake.us

-111.11Visit Site
Stake.us

Under 43.5

at Stake.us

-111.11Visit Site
Leigh Copson
Leigh Copson

Sports Editor25+ Years Experience, US & Combat Sports Specialist

During his career he has covered some of the biggest sporting events on the planet, including the Super Bowl, the Champions League Final and the World Cup Final. He has also covered almost every major boxing match and UFC fight card during this time.. His specialist sports are American Football, Basketball, Ice Hockey, Boxing, Mixed Martial Arts and Football.


Follow more of Leigh's work on Muckrack.

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