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Home / College Football / Northwestern at Indiana Predictions & Picks – Hoosiers’ College Football Cover Drought To Continue

Northwestern at Indiana Predictions & Picks – Hoosiers’ College Football Cover Drought To Continue

Quick Read

  • Indiana undefeated but 0-3 against the spread
  • Northwestern in good form, tipped to cover
  • Recommended: Wildcats +21.5 and Under 49.5 points
Leigh Copson
Written by Leigh Copson
Sports Editor25+ Years Experience, US & Combat Sports Specialist
Updated: Sep 21, 2026
ncaaf northwestern indiana
Our TipStrong confidence
Stake.us

Spread

Indiana -21.5

Odds

-111.11

Place Bet
Stake.us

Total Points

Under 49.5

Odds

-111.11

Place Bet

Northwestern at Indiana Predictions & Picks

Northwestern are tipped to cover as a three-touchdown underdog in Indiana.

The Hoosiers are the better team and are expected to win, but they are yet to cover this season and the Wildcats have the talent on both sides of the football to prevent a total blowout.

  • Indiana are 0-3-0 ATS this season
  • Northwestern are 2-0-0 ATS in 2026 so far
  • The Under has cashed in 2 of Indiana’s 3 games so far

Head To Head

  • Northwestern lead the all-time series 47-36-1
  • Indiana won 41-24 when the two teams last met in October 2024

Northwestern Form

Northwestern go into their first Big Ten game of the season having won back-to-back non-conference matchups to start the season.

The Wildcats opened with a 34-17 win over South Dakota State, and backed that up in impressive fashion last weekend as they blew out Colorado.

They raced out to a 21-0 lead before half-time, before putting the finishing touches on a 41-7 victory in the second half.

Northwestern quarterback Aidan Chiles went 17/22 for 241 yards and three touchdowns, with Joseph Williams leading the receivers with 88 yards and a score off five receptions.

No less than nine players carried the football, with lead backs Gavin Sawchuk and Caleb Komolafe combining for 97 yards on the ground.

Indiana Form

Indiana have made the perfect start to their defence of the national crown, winning three straight games.

The Hoosiers kicked off the campaign with a 52-16 victory over North Texas – and since then they have not given up a single point.

They made it back-to-back wins with a 55-0 shutout of Howard, before downing Western Kentucky 38-0 last weekend.

Indiana quarterback Josh Hoover went 18/24 for 273 yards and two touchdowns, while Charlie Becker led the receivers with 127 yards and a TD.

Lee Beebe rushed for 50 yards and a couple of touchdowns, but it was Turbo Richard who made the biggest impact on the ground, amassing 149 yards and a score off 15 carries.

Verdict

Indiana are off to perfect start, but they are yet to cover the spread this season.

Northwestern are in good form and are playing good football, so we are taking the Wildcats and the free points on Friday night.

Stake.us
Top Pick

Indiana -21.5

at Stake.us

-111.11Visit Site
Stake.us

Under 49.5

at Stake.us

-111.11Visit Site
Leigh Copson
Leigh Copson

Sports Editor25+ Years Experience, US & Combat Sports Specialist

Leigh Copson is the editor of expert picks and provides daily picks for the NFL, NBA, NHL, MLB boxing and MMA. He provides analysis of the big events across major American leagues every day.


He started out with the Press Association before moving online and working for ExpertPicks.com, FreeTips.com and other sports news and betting sites. 

He has covered some of the biggest sporting events on the planet, including the Super Bowl, the Champions League Final and the World Cup Final and has covered almost every major boxing match and UFC fight card during this time.

Follow more of Leigh's work on Muckrack and connect with him on LinkedIn.


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