Penn State at Northwestern Predictions & Picks
Northwestern are tipped to cover as a betting underdog at home.
The Wildcats are off to an impressive start and put up a very credible performance in the one-score loss to Indiana, while Penn State just got embarrassed at home by Wisconsin.
- Northwestern are 3-0-0 ATS this season
- Penn State are 0-1-0 ATS on the road this season
- Northwestern are 4-2-0 ATS in the previous 6 meetings
- The Under has cashed in 3 of the last 4 meetings
Head To Head
- Penn State leads the all-time series 16-6
- Northwestern won 22-21 when the two teams last met in October 2025
Penn State Form
Penn State go into this game looking to rebound from a shock defeat that dropped them to 3-1.
The Nittany Lions opened the 2026 season at home to Marshall, and they posted a shutout as they won the matchup 45-0.
They backed that up in their road opener as they travelled to Temple and recorded a 27-9 victory.
Penn State made it three-in-a-row a week later, as they recorded another home blowout in the form of a 55-13 demolition of Buffalo.
However, the Nittany Lions' perfect start was brought to a shuddering halt in their Big Ten opener, as they suffered a 24-20 home defeat to Wisconsin.
Northwestern Form
Northwestern enter this matchup on the back of their first defeat of the season, which dropped them to 2-1.
The Wildcats kicked off the campaign with back-to-back non-conference games at home, and ran out convincing winners in both.
They kicked things off with a 34-18 victory when they played host to South Dakota State.
Northwestern then followed that up with a 41-7 blowout of Colorado, before heading out on the road for their Big Ten opener.
The Wildcats could not have asked for a tougher conference opener, but they earned plenty of plaudits as they ran defending national champions Indiana close in a 29-23 defeat.