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Home / NFL / Carolina Panthers at Arizona Cardinals Preview & Picks – Cardinals To Take NFL Home Opener

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Carolina Panthers at Arizona Cardinals Preview & Picks – Cardinals To Take NFL Home Opener

Quick Read

  • Carolina Panthers at Arizona Cardinals picks for Sunday, September 14
  • Game is taking place at State Farm Stadium
  • Preview, predictions, stats & form
Leigh Copson
Written by Leigh Copson
Sports Editor25+ Years Experience, US & Combat Sports Specialist
Updated: Sep 11, 2025
arizona cardinals

(Getty Images)

Carolina Panthers at Arizona Cardinals Preview & Picks

Arizona are tipped to cover as they win their home opener.

The Cardinals were efficient as they won on the road a week ago, while Carolina struggled in all areas and turned the ball over repeatedly on offense.

  • Arizona Cardinals are 5-1-0 ATS in their last 6 home games
  • Carolina Panthers are 2-15 in their previous 17 road games
  • Carolina Panthers are 4-14-0 ATS in their last 18 road games
  • The Under cashed in both teams’ season opener

Head To Head

  • Carolina Panthers lead the all-time series 15-6
  • Carolina Panthers won 36-30 in overtime when the two teams last met in December 2024

Carolina Panthers Form

Carolina head out on the road for the second week in a row looking to get their first win of the season.

The Panthers’ playoff drought reached seven seasons in 2024 as they won just five times, and if their 2025 opener is anything to go by, that drought will reach eight seasons.

Bryce Young got the start last Sunday, having been benched and then reinstalled as starting quarterback during the 2024 campaign.

The Carolina QB had a rough day at the offense though as he threw for just 154 yards, with one touchdown and two interceptions.

The Panthers struggled to get anything going on the ground too, and that resulted in a 26-10 defeat at the hands of Jacksonville.

Arizona Cardinals Form

Arizona enter their home opener looking to follow up last weekend’s road win in New Orleans.

The Cardinals suffered their third straight losing season in 2024, but having finished 4-13 in each of the previous two campaigns, their 8-9 record was an improvement.

That record would have been much better had their form not collapsed late in the season, as they lost five of their final seven games to miss out on the postseason.

Arizona did wrap up the campaign on a positive note though, beating San Francisco, and they picked up from where they left off last weekend.

The Cardinals kicked of the 2025 season with a 20-13 victory over the Saints in New Orleans.
Leigh Copson
Leigh Copson

Sports Editor25+ Years Experience, US & Combat Sports Specialist

During his career he has covered some of the biggest sporting events on the planet, including the Super Bowl, the Champions League Final and the World Cup Final. He has also covered almost every major boxing match and UFC fight card during this time.. His specialist sports are American Football, Basketball, Ice Hockey, Boxing, Mixed Martial Arts and Football.


Follow more of Leigh's work on Muckrack.

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