Iowa State at BYU Predictions & Picks
BYU are tipped to cover a double digit spread as they beat Iowa State.
The Cougars can lean on their run game and the altitude to wear down a Cyclones defense that has been gashed in back-to-back outings.
And on the opposite side of the football, this BYU defense can put the clamps on a visiting offense that has struggled to put points on the board against AP ranked teams.
- BYU are 4-0 this season
- BYU are 4-0-0 ATS so far in 2026
- Iowa State have averaged just 15 points per game on the road
- The Under has cashed in 2 of BYU’s last 3 games
Head To Head
- Iowa State lead the all-time series 5-1
- BYU won 41-27 when the two teams last met in October 2025
Iowa State Form
Iowa State head to Brigham Young looking to build on last week’s victory and record back-to-back wins for the first time this season.
The Cyclones made a winning start to the campaign as they downed Southeast Missouri State 38-10.
They failed to follow that up a week later though, although they defied pre-game expectations in a narrow 16-13 defeat at rivals Iowa.
Iowa State rebounded with a 55-7 blowout of Bowling Green, only to then fall 31-17 at home to Utah a week later.
The Cyclones did avoid back-to-back defeats though, as they edged West Virginia 45-42 last weekend to improve to 3-2.
BYU Form
BYU enter this matchup having won their first two Big 12 matchups to take their overall record to 4-0.
The Cougars kicked off the campaign with a blowout victory over Utah Tech, beating their overmatched opponent 63-7.
They faced more of a challenge in their Big 12 opener, but they enjoyed a successful start to their conference schedule as they beat Arizona 28-17.
BYU returned to non-conference action a week later and improved to 3-0 with a 41-23 victory at Colorado State.
The Cougars then made it four-in-a-row last time out as they went out on the road to down TCU, 17-10.