Hamilton enter this matchup with the defending champions having now lost their last three games to fall to 3-6.
The Tiger-Cats endured a losing start to the season as they lost to Montreal in overtime at home, 30-27.
They rebounded on the road with a 37-27 victory in Winnipeg, and followed that up a week later as they went into the bye week on the back of a 41-27 win over the BC Lions.
Hamilton failed to keep that run going after the break as they lost 14-13 to Winnipeg and 38-7 in Saskatchewan, but they did avoid a third straight loss as they downed Toronto 24-23.
The Tiger-Cats have not won since though, sandwiching a 44-20 home loss to Calgary with road defeats to Montreal, 31-18, and the BC Lions, 27-24.