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Home / NFL / Buffalo Bills at Los Angeles Rams Predictions & Picks – Rams To Win Monday NFL Shootout

Buffalo Bills at Los Angeles Rams Predictions & Picks – Rams To Win Monday NFL Shootout

  • Los Angeles predicted to win and cover spread against Buffalo
  • Buffalo's recent offensive miscues and defensive problems are highlighted
  • Rams' offense is expected to exploit the Bills’ struggling defense
Leigh Copson
By Leigh Copson • Sports Editor
25+ Years Experience, US & Combat Sports Specialist
Updated:
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nfl bills rams
Our Tip
Stake.com

Spread

Los Angeles -3.5

Odds

-105.26

Place Bet
Stake.com

Total Points

Over 54.5

Odds

-111.11

Place Bet

Buffalo Bills at Los Angeles Rams Predictions & Picks

Los Angeles are tipped to cover as they win a Monday Night Football shootout.

Buffalo’s offense has been sloppy with the football over the past couple of games, while the defense has been a real problem for them through four weeks.

Matthew Stafford, Puka Naku et al. can take full advantage to come away with the victory.
  • Los Angeles Rams are 2-0-0 ATS in their 2 wins
  • Buffalo Bills are coming off a home defeat to New England
  • Los Angeles Rams are 7-2-0 ATS in their last 9 games at SoFi Stadium
  • The Over has cashed in each of Los Angeles’ last 2 games
  • The Over has hit in 3 of Buffalo’s 4 games this season

Head To Head

  • Buffalo Bills lead the all-time series 9-6
  • Los Angeles Rams won 44-42 when the two teams last met in December 2024

Buffalo Bills Form

Buffalo make the long trip to California looking to rebound from their first defeat of the season, which dropped them to 3-1.

The Bills kicked off the campaign on the road and enjoyed a successful start as they beat Houston 36-31.

They then followed that up in their home opener as they marked the official opening of their new stadium with a 41-31 victory over Detroit.

Buffalo made it three-in-a-row with a 25-16 win against the Los Angeles Chargers, but that would prove to be the end of their win streak.

The Bills hosted division rivals New England last weekend, and suffered a surprise 29-26 defeat to the Patriots.

Los Angeles Rams Form

Los Angeles return home looking to win back-to-back games for the first time this season.

The Rams opened the season by making the long trip to Australia for a showdown with division rivals San Francisco, and their travel plans appeared to backfire on them.

They lost that matchup 27-7, but rebounded the following week with a 28-6 success when they hosted the New York Giants.

Los Angeles failed to make it consecutive wins as they then fell 30-26 in Denver, but they did issue an immediate response.

The Rams returned to winning ways last Sunday as they travelled to Philadelphia and downed the Eagles, 24-20.

Verdict

Los Angeles have struggled for consistency so far, but the return of Nacua is a big boost for this offense, and they now get to face a struggling Bills defense.

The Rams can light up the visitors in this one, ensuring they come out on the winning end of what could be a high-scoring shootout.

Stake.com
Top Pick

Los Angeles -3.5

at Stake.com

-105.26Visit Site
Stake.com

Over 54.5

at Stake.com

-111.11Visit Site
Leigh Copson
Leigh Copson

Sports Editor • 25+ Years Experience, US & Combat Sports Specialist

US sports writer covering the NFL, NBA, NHL, boxing and MMA, with previews, predictions and betting tips across the major American leagues.


During his career at the Press Association and online sports sites including FreeTips and ExpertPicks.com, he has covered some of the biggest sporting events on the planet, including the Super Bowl, the Champions League Final and the World Cup Final.

He has also covered almost every major boxing match and UFC fight card during this time.. His specialist sports are American Football, Basketball, Ice Hockey, Boxing, Mixed Martial Arts and Football.

Follow more of Leigh's work on Muckrack and connect with him on LinkedIn.

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