Get Free Alerts

Never miss a tip. Choose your sports and get instant updates.

Football

Football

8 active tips

Basketball

Basketball

1 active tip

Cricket

Cricket

1 active tip

Tennis

Tennis

1 active tip

Esports

Esports

1 active tip

Free forever. No spam. Unsubscribe anytime by leaving the channel.

Home / College Football / Syracuse at Pitt Predictions & Picks – Panthers To Cover In College Football Conference Win

Syracuse at Pitt Predictions & Picks – Panthers To Cover In College Football Conference Win

Quick Read

  • Pitt is favored to cover the spread (-10.5) vs Syracuse
  • Strong Panthers defense and home advantage key factors
  • Under 51.5 points recommended based on matchup trends
Leigh Copson
Written by Leigh Copson
Sports Editor25+ Years Experience, US & Combat Sports Specialist
Updated: Sep 16, 2026
ncaaf syracuse pitt
Our TipStrong confidence
Stake.us

Spread

Pitt -10.5

Odds

-111.11

Place Bet
Stake.us

Total Points

Under 51.5

Odds

-111.11

Place Bet

Syracuse at Pitt Predictions & Picks

Pitt are tipped to cover as they maintain their perfect record and win their ACC opener.

The Panthers’ stout run game can force Steve Angeli to try to win this with his arm – a potential recipe for disaster for the visitors after he threw three picks in last week’s loss to Cal.

  • Pitt are 2-0 so far this season
  • Syracuse are 0-1-0 ATS against ACC opposition
  • Pitt are 7-1 in the previous 8 meetings
  • Pitt are 8-2-0 ATS in the previous 10 meetings
  • The Under has cashed in 6 of the previous 7 meetings

Head To Head

  • Pitt lead the all-time series 45-33-3
  • Pitt won 30-13 when the two teams last met in October 2025

Syracuse Form

Syracuse head to Pitt on a short week and on the back of their first defeat of the 2026 season.

The Orangemen kicked off their campaign with a 66-3 non-conference win over New Hampshire, but failed to follow that up in their opening ACC encounter.

They played host to Cal last weekend, and suffered a 21-18 defeat at the hands of the Golden Bears.

Quarterback Steve Angeli completed less than 50% of his 50 passing attempts, and racked up three interceptions in the loss.

An ill-disciplined performance all round saw Syracuse commit 14 penalties for a total of 110 yards.

Pitt Form

Pitt go in their first conference matchup of the season having opened with back-to-back non-conference successes.

The Panthers recorded a blowout victory as they downed Miami Ohio 59-14 in their opening game.

They then backed that up last weekend as they scraped past UCF, beating their opposition from the Big 12, 12-7.

Quarterback Mason Heintschel went 18/29 for 212 yards, with Cataurus Hicks on the receiving end of 64 of those yards.

Damon Ferguson led the way on the ground, carrying the ball 20 times for 59 yards and a touchdown, while adding 27 yards receiving.

Verdict

Our Verdict
Both teams are coming off underwhelming performances, but Pitt did win and they have home advantage on a short week.

If the offense can keep things clean, the Panthers can lean on their defense to get the job done.

Stake.us
Top Pick

Pitt -10.5

at Stake.us

-111.11Visit Site
Stake.us

Under 51.5

at Stake.us

-111.11Visit Site
Leigh Copson
Leigh Copson

Sports Editor25+ Years Experience, US & Combat Sports Specialist

During his career he has covered some of the biggest sporting events on the planet, including the Super Bowl, the Champions League Final and the World Cup Final. He has also covered almost every major boxing match and UFC fight card during this time.. His specialist sports are American Football, Basketball, Ice Hockey, Boxing, Mixed Martial Arts and Football.


Follow more of Leigh's work on Muckrack.

Read More