New York have undergone major coaching changes after winning just four of their games last season.
The pressure was on Giants head coach Brian Daboll heading into the season, and he was given his marching orders after a late collapse in Chicago left them 2-8.
That was their fifth straight defeat, and that losing skid reached nine games before they finally snapped that sequence with back-to-back wins to close out the season.
New York moved quickly in the offseason to name John Harbaugh as the new head coach, and he has brought in Matt Nagy as his offensive co-ordinator from Kansas City.
The Giants warmed up for the new season by going 1-2 in pre-season, rebounding from a 13-10 home loss to Minnesota with home wins against Miami, 26-3, and the New York Jets, 23-6.