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San Francisco Giants at San Diego Padres Preview & Picks – Padres To Take Down Giants Again In MLB

leigh-copson
20 Aug 2025
leigh-copson
Leigh Copson 20 Aug 2025
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  • San Francisco Giants at San Diego Padres picks for Wednesday, August 20
  • Game is taking place at Petco Park
  • Preview, predictions, stats & form
(Getty Images)
    San Francisco Giants at San Diego Padres Preview & Picks
  • San Francisco Giants at San Diego Padres Preview & Picks
  • Head To Head
  • San Francisco Giants Form
  • San Diego Padres Form

San Francisco Giants at San Diego Padres Preview & Picks

San Diego are backed to win the penultimate game of this series with San Francisco.

The Padres are the team in better form and they boast a strong recent track record against the Giants, while the visitors are sending out a pitcher who took a beating last time out.

  • San Diego Padres are 9-3 in the last 12 meetings
  • San Francisco Giants are 2-8 in their last 10 games
  • Giants pitcher Landen Roupp allowed 5 hits & 5 runs in 3 innings last time out
  • The two starting pitchers have a combined ERA of 12.45 as starters

Head To Head

  • San Francisco Giants lead the all-time series 497-459
  • San Diego Padres won 5-1 when the two teams last met on August 19

San Francisco Giants Form

San Francisco entered this series with San Diego on the back of a victory, but having lost their eight games prior to that.

The Giants won five of their first seven games this month, only to see their form cool off massively after a 5-0 victory over Washington.

They dropped the next two games against the Nationals, 4-2 and 8-0, and that proved to be the start of a seven-game losing skid.

San Francisco were then swept at home by San Diego, losing 4-1, 5-1 and 11-1 to the Padres, before losing the first two games of the series with Tampa Bay, 7-6 and 2-1.

The Giants rallied to win the series finale, 7-1, and backed that up with a 4-3 win over San Diego in the opening game of this series, but they failed to back that up on Tuesday as they fell 5-1 to the Padres.

San Diego Padres Form

San Diego returned home for this series having been swept by the Los Angeles Dodgers last weekend, but they had won nine of their previous 15 games.

The Padres began the month by winning 4-1 and 7-3 either side of an 8-5 loss to St Louis, and they then moved on to Arizona where they responded to a 6-2 loss with 10-5 and 3-2 wins.

Then then returned home for a series against Boston, and bounced back from a 10-2 loss to the Red Sox by with 5-1 and 6-2 wins over the visitors.

San Diego backed that up as they then travelled to San Francisco to sweep the Giants with 4-1, 5-1 and 11-1 wins.

The Padres' good run was halted as they lost 3-2, 6-0 and 5-4 to the Dodgers, and they then dropped the series opener against San Francisco 4-3, but they rallied to take last night's meeting, 5-1.

Verdict

San Diego brought an end to their losing skid last night and we expect them to back up that victory.

They can get after San Francisco starter Roupp and maintain their strong recent record against the Giants.

Best Bet1: San Diego -1.5 Line @135.00 at Stake.us - 3 Units
Best Bet2: Over 8.5 Total Runs @-116.28 at Stake.us - 3 Units
San Diego -1.5
Line
@135.00 - 3 Units
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Bet at Stake.us
Over 8.5
Total Runs
@-116.28 - 3 Units
55 Stake Cash no deposit & 550,000 Gold Coins & 5% Rakeback
Use promo code NEWBONUS

Sign up with the code NEWBONUS. When you verify your account get 25 Stake Cash for free PLUS 250,000 Gold Coins and 5% Rakeback! No deposit required. Login each day for the next 30 days and get an additional 30 Stake Cash AND 300,000 Gold Coins. 21+ only. T&Cs apply. Excludes WA, NY, NV, ID, KY, MI, VT, NJ, DE, WV, PA, RI & MD.

Bet at Stake.us