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USC at Notre Dame Preview & Picks – Take Trojans & Free Points In Notre Dame College Football Clash
- USC at Notre Dame picks for Saturday, October 18
- Game is taking place at Notre Dame Stadium
- Preview, predictions, stats & form
(Getty Images )
- USC at Notre Dame Preview & Picks
- Head To Head
- USC Form
- Notre Dame Form
USC at Notre Dame Preview & Picks
USC at Notre Dame Preview & Picks
USC are backed to cover as a betting underdog in South Bend.
The Trojans’ offense is rolling with Jayden Maiava at the controls, and this defense is strong against the run, which Notre Dame have leaned on heavily during their win streak.
- Notre Dame are 1-2-0 ATS as a single digit favorite
- USC Trojans are 3-1-0 ATS in their last 4 games as a betting underdog
- The Over has hit in 4 of Notre Dame’s first 6 games
- The Over has cashed in 4 of USC’s 6 games so far
Head To Head
- Notre Dame lead the all-time series 52-37-5
- Notre Dame won 49-35 when they two teams last met in November 2024
USC Form
USC head back out on the road having rebounded from their first defeat of the season to improve to 5-1 last time out.
The Trojans opened up with back-to-back non-conference games at home, beating Missouri State 73-13 and Georgia Southern 59-20.
They then kicked off their Big Ten schedule with a 33-17 victory at Purdue, before heading back home to down Michigan State, 45-31.
USC failed to make it three-in-a-row in conference play though, as they fell to a 34-32 defeat at Illinois.
The Trojans did deliver a swift and strong response to that setback however, as they travelled to Ann Arbor last weekend and knocked off ranked Michigan, winning 31-13.
Notre Dame Form
Notre Dame enter this matchup looking to extend their win streak to five games and beat a ranked team for the first time this season.
The Fighting Irish, who lost in last season’s National Championship, opened the 2025 campaign with back-to-back defeats against AP-ranked teams.
They were beaten 27-24 at Miami on opening night, before returning home for a 41-40 loss at the hands of Texas A&M.
Notre Dame finally got off the mark against Purdue though, winning 56-30, and they backed that up on the road a week later as they beat Arkansas 56-13.
The Fighting Irish then extended their win streak to four games with two more home wins, downing Boise State 28-7 and NC State 36-7.
Verdict
Notre Dame have been rolling over the past several weeks, but we like USC and the free points.
The Trojans can slow down this Fighting Irish run game, while the offense puts up enough points to at least take this game down to the wire.
The Trojans can slow down this Fighting Irish run game, while the offense puts up enough points to at least take this game down to the wire.
USC +9.5
Spread
@-111.11 - 4 Units
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Over 61.5
Total Points
@-111.11 - 2 Units
55 Stake Cash no deposit & 550,000 Gold Coins & 5% Rakeback
Use promo code NEWBONUS
Sign up with the code NEWBONUS. When you verify your account get 25 Stake Cash for free PLUS 250,000 Gold Coins and 5% Rakeback! No deposit required. Login each day for the next 30 days and get an additional 30 Stake Cash AND 300,000 Gold Coins. 21+ only. T&Cs apply. Excludes WA, NY, NV, ID, KY, MI, VT, NJ, DE, WV, PA, RI & MD.
See also
- LSU at Vanderbilt Preview & Picks – Commodores To Contain Toothless Tigers Offense In College Football Win
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- Ole Miss at Georgia Preview & Picks – Bulldogs To Take Bite Out Of Rebels In Key College Football Clash
- Ohio State at Wisconsin Preview & Picks – Buckeyes To Beat Down Badgers In College Football
- Louisville at Miami FL Preview & Picks – Hurricanes To Keep Perfect College Foorball Record Intact
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