Cleveland Guardians at Seattle Mariners Predictions & Picks – Mariners To Win MLB Opener

leigh-copson
2 hours ago
Leigh Copson 2 hours ago
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  • Cleveland Guardians at Seattle Mariners picks for Thursday, March 26
  • Game is taking place at T-Mobile Park
  • Preview, predictions, stats & form
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Cleveland Guardians at Seattle Mariners Predictions & Picks

Seattle are tipped to open their campaign with a victory at home.

Cleveland starter Tanner Bibee struggled during spring, and the Mariners can take advantage to get their playoff quest off to a winning start.

  • Seattle Mariners are 4-2 in the previous 6 meetings
  • Seattle Mariners swept Cleveland in a 3-game home series last season
  • The Over has cashed in 7 of the previous 10 meetings

Head To Head

  • Cleveland Guardians lead the all-time series 250-207
  • Seattle Mariners won 4-2 when the two teams last met in August 2025

Cleveland Guardians Form

Cleveland enter the 2026 campaign looking to top their previous campaign, where they made it to the postseason only to fall at the first hurdle.

The Guardians recorded 88 wins during the regular season to finish to of the AL Central and set up a Wild Card meeting with Detroit.

They rebounded from a 2-1 defeat to the Tigers with a 6-1 victory that set up a decider, but they failed to back up that success as they lost the winner-takes-all clash, 6-3.

Cleveland will look to go much deeper in the postseason this time around, and they warmed up for the new campaign by going 16-14 in spring training.

Seattle Mariners Form

Seattle have their sights on bettering last season’s run and winning the World Series this time around.

The Mariners were one of the best performing teams in the 2025 regular season, reeling off 90 victories to finish top of the AL West standings and earn a playoff bye.

They faced Detroit in the AL Division Series, and after splitting the first four games with the Tigers they clinched thanks to a 3-2 victory at home.

Seattle made a much stronger start in the Championship Series, winning their first two games against Toronto, but they collapsed after that and lost four of the next five to bow out of the postseason.

The Mariners have prepared for the new campaign by going 11-19 during spring training.

Verdict

Losing a two-game lead in the Championship Series left a sour taste in Seattle’s mouth, and they will be determined to erase that this season.

The Mariners can get their quest off to a winning start at the expense of the Guardians.

Best Bet1: Seattle -1.5 Line @125.00 at Stake.us - 3 Units
Best Bet2: Over 6.5 Total Runs @-120.48 at Stake.us - 3 Units
Seattle -1.5
Line
@125.00 - 3 Units
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Bet at Stake.us
Over 6.5
Total Runs
@-120.48 - 3 Units
55 Stake Cash no deposit & 550,000 Gold Coins & 5% Rakeback
Use promo code NEWBONUS

Sign up with the code NEWBONUS. When you verify your account get 25 Stake Cash for free PLUS 250,000 Gold Coins and 5% Rakeback! No deposit required. Login each day for the next 30 days and get an additional 30 Stake Cash AND 300,000 Gold Coins. 21+ only. T&Cs apply. Excludes WA, NY, NV, ID, KY, MI, VT, NJ, DE, WV, PA, RI & MD.

Bet at Stake.us

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