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Cleveland Cavaliers at New York Knicks Preview & Picks – Cavs To Open With ‘Big Apple’ NBA Win

leigh-copson
22 Oct 2025
leigh-copson
Leigh Copson 22 Oct 2025
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  • Cleveland Cavaliers at New York Knicks picks for Wednesday, October 22
  • Game is taking place at Madison Square Garden
  • Preview, predictions, stats & form
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    Cleveland Cavaliers at New York Knicks Preview & Picks
  • Cleveland Cavaliers at New York Knicks Preview & Picks
  • Head To Head
  • Cleveland Cavaliers Form
  • New York Knicks Form

Cleveland Cavaliers at New York Knicks Preview & Picks

Cleveland are tipped to open the season with a victory in New York.

The Cavaliers return with a stacked roster that is arguably better than last season’s, which was able to sweep New York.

  • Cleveland Cavaliers were 4-0 against New York last season
  • Cleveland Cavaliers were 4-0-0 ATS against the Knicks in 2024/25
  • New York Knicks have lost their 7 season openers as a betting underdog
  • The Under has cashed in 9 of the previous 10 meetings

Head To Head

  • New York Knicks lead the all-time series 133-111
  • Cleveland Cavaliers won 108-102 when the two teams last met on April 11

Cleveland Cavaliers Form

Cleveland enter the new season once again looking to challenge for the NBA Championship once again.

The Cavaliers fell short last time around, exiting in the conference semi-finals for the second straight year, but they return a stacked roster that includes defensive player of the year Evan Mobley.

They are also again led by Kenny Atkinson, who earned coach of the year honours last season.

Cleveland won just one of their four games during the pre-season, which opened with back-to-back losses against Chicago, 118-117 at home and 119-112 on the road.

The Cavaliers then fell 138-107 in Boston, before avoiding a winless pre-season with a 118-100 victory at home to Detroit.

New York Knicks Form

New York go into their season opener looking to hand new head coach Mike Brown a winning debut.

The Knicks made it all the way to the Eastern Conference Finals last season, where the lost in six games to Indiana.

Despite that deep playoff run they fired head coach Tom Thibodeau in the offseason, replacing him with Brown.

New York went 4-1 in pre-season under their new head coach; kicking things off with back-to-back wins over Philadelphia, 99-84 and 113-104.

The Knicks then beat Minnesota in overtime, 100-95, before rebounding from a 120-103 loss to Washington with a 113-108 victory over Charlotte.

Verdict

Cleveland return with a roster capable of going all the way and winning the NBA championship.

The Cavaliers owned New York last season, and we expect them to continue that ownership in their 2025/26 opener.

Best Bet1: Cleveland Win Moneyline @-111.11 at Stake.us - 4 Units
Best Bet2: Under 228.5 Total Points @-111.11 at Stake.us - 2 Units
Cleveland Win
Moneyline
@-111.11 - 4 Units
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Bet at Stake.us
Under 228.5
Total Points
@-111.11 - 2 Units
55 Stake Cash no deposit & 550,000 Gold Coins & 5% Rakeback
Use promo code NEWBONUS

Sign up with the code NEWBONUS. When you verify your account get 25 Stake Cash for free PLUS 250,000 Gold Coins and 5% Rakeback! No deposit required. Login each day for the next 30 days and get an additional 30 Stake Cash AND 300,000 Gold Coins. 21+ only. T&Cs apply. Excludes WA, NY, NV, ID, KY, MI, VT, NJ, DE, WV, PA, RI & MD.

Bet at Stake.us