Michigan vs Saint Louis Predictions & Picks – Wolverines’ Cover Struggles To Continue In March Madness

leigh-copson
20 Mar 2026
Leigh Copson 20 Mar 2026
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  • Michigan vs Saint Louis picks for Saturday, March 21
  • Game is taking place at KeyBank Center in Buffalo, New York
  • Preview, predictions, stats & form
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Michigan vs Saint Louis Predictions & Picks

Michigan’s cover troubles are tipped to continue in the second round of March Madness.

The Wolverines have rarely covered the spread over the past couple of months, while this well-rounded Billikens group shoots the three-ball and can pose plenty of problems.

  • Michigan are 1-8-0 ATS in their last 9 games
  • Saint Louis are 2-0-0 ATS as a betting underdog this season
  • Michigan are 3-6-0 ATS in their 9 neutral venue games
  • The Over cashed in both teams’ first round matchups

Head To Head

  • Michigan lead the all-time series 1-0
  • Michigan won 80-78 when the two teams last met in December 1970

Michigan Form

DateOppositionW/LScoreCompetition
Feb-17 Purdue W 91-80 Regular Season
Feb-21 Duke L 63-68 Regular Season
Feb-24 Minnesota W 77-67 Regular Season
Feb-27 Illinois W 84-70 Regular Season
Mar-05 Iowa W 71-68 Regular Season
Mar-08 Michigan State W 90-80 Regular Season
Mar-13 Ohio State W 71-67 Conference Tournament
Mar-14 Wisconsin W 68-65 Conference Tournament
Mar-15 Purdue L 72-80 Conference Tournament
Mar-19 Howard W 101-80 NCAA Tournament

Saint Louis Form

DateOppositionW/LScoreCompetition
Feb-13 Loyola IL W 86-59 Regular Season
Feb-17 Rhode Island L 76-81 Regular Season
Feb-20 VCU W 88-75 Regular Season
Feb-24 Dayton L 62-77 Regular Season
Feb-28 Duquesne W 91-76 Regular Season
Mar-04 Loyola IL W 79-65 Regular Season
Mar-07 George Mason L 57-86 Regular Season
Mar-13 George Washington W 88-81 Conference Tournament
Mar-14 Dayton L 69-70 Conference Tournament
Mar-19 Georgia W 102-77 NCAA Tournament

Verdict

Michigan continue to find ways to get the job done, and that is likely to be the case again here.

However, the Wolverines have covered just once in their last nine games and have not covered as a double-digit favourite in over a month, so give us Saint Louis and the points.

Best Bet1: Saint Louis +12.5 Spread @-111.11 at Stake.us - 4 Units
Best Bet2: Over 161.5 Total Points @-111.11 at Stake.us - 2 Units
Saint Louis +12.5
Spread
@-111.11 - 4 Units
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Bet at Stake.us
Over 161.5
Total Points
@-111.11 - 2 Units
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Sign up with the code NEWBONUS. When you verify your account get 25 Stake Cash for free PLUS 250,000 Gold Coins and 5% Rakeback! No deposit required. Login each day for the next 30 days and get an additional 30 Stake Cash AND 300,000 Gold Coins. 21+ only. T&Cs apply. Excludes WA, NY, NV, ID, KY, MI, VT, NJ, DE, WV, PA, RI & MD.

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