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Penn State at Ohio State Preview & Picks – Buckeyes To Power Past Penn State In College Football

leigh-copson
27 Oct 2025
leigh-copson
Leigh Copson 27 Oct 2025
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  • Penn State at Ohio State picks for Saturday, November 1
  • Game is taking place at Ohio Stadium
  • Preview, predictions, stats & form
(Getty Images)
    Penn State at Ohio State Preview & Picks
  • Penn State at Ohio State Preview & Picks
  • Head To Head
  • Penn State Form
  • Ohio State Form

Penn State at Ohio State Preview & Picks

Ohio State are tipped to cover the spread once again this Saturday.

The Buckeyes’ well round offense and dominant defense is expected to be too much for a badly out-of-form Penn State team that are stacking up losses and rarely cover.

  • Ohio State are 6-0-1 ATS in their last 7 games
  • Ohio State are 4-0-0 ATS as a double digit favorite
  • Penn State are 1-6-0 ATS in their 7 games so far
  • The Over has cashed in 5 of Penn State’s 7 games

Head To Head

  • Ohio State lead the all-time series 24-8
  • Ohio State won 20-13 when the two teams last met in November 2024

Penn State Form

Penn State go into this matchup having now lost four consecutive games to fall to 3-4 on the season.

The Nittany Lions kicked off the season with three straight wins against non-conference opposition, beating Nevada 46-11, Florida International 34-0 and Villanova 52-6.

However, once their Big Ten schedule began their form collapsed, costing head coach James Franklin his job.

Penn State lost 30-24 at home to Oregon, and then went on to suffer a 42-37 defeat at home to UCLA and a 22-21 loss at home to Northwestern.

Franklin was fired after the loss to the Wildcats, but his departure did not spark an improvement in fortunes as the Nittany Lions lost 25-24 at Iowa last time out.

Ohio State Form

Ohio State remain the number one ranked team in the nation, having won each of their first seven games.

The Buckeyes started the season as the number three ranked team according to AP, despite being the defending national champions, but they answered that disrespect in emphatic fashion.

They beat top-ranked Texas 14-7 on opening weekend, and backed that up with further non-conference wins over Grambling State, 70-0, and Ohio, 37-9.

Ohio State then kicked off their Big Ten schedule with a 24-6 victory at Washington, before returning home to blow out Minnesota, 42-3.

The Buckeyes then went back out on the road for their last two games and beat Illinois 34-16 and Wisconsin 34-0.

Verdict

Ohio State’s offense continues to roll and the defense has now kept six of their seven opponents to under 10 points.

We simply cannot ignore this level of dominance, so we expect a Buckeyes win and cover.

Best Bet1: Ohio State -20.5 Spread @-111.11 at Stake.us - 4 Units
Best Bet2: Over 43.5 Total Points @-111.11 at Stake.us - 2 Units
Ohio State -20.5
Spread
@-111.11 - 4 Units
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Bet at Stake.us
Over 43.5
Total Points
@-111.11 - 2 Units
55 Stake Cash no deposit & 550,000 Gold Coins & 5% Rakeback
Use promo code NEWBONUS

Sign up with the code NEWBONUS. When you verify your account get 25 Stake Cash for free PLUS 250,000 Gold Coins and 5% Rakeback! No deposit required. Login each day for the next 30 days and get an additional 30 Stake Cash AND 300,000 Gold Coins. 21+ only. T&Cs apply. Excludes WA, NY, NV, ID, KY, MI, VT, NJ, DE, WV, PA, RI & MD.

Bet at Stake.us