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Vanderbilt at South Carolina Preview & Picks – Vandy To Record College Football Cover

leigh-copson
10 Sep 2025
leigh-copson
Leigh Copson 10 Sep 2025
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  • Vanderbilt at South Carolina picks for Saturday, September 13
  • Game is taking place at Williams-Brice Stadium
  • Preview, predictions, stats & form
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    Vanderbilt at South Carolina Preview & Picks
  • Vanderbilt at South Carolina Preview & Picks
  • Head To Head
  • Vanderbilt Form
  • South Carolina Form

Vanderbilt at South Carolina Preview & Picks

Vanderbilt are tipped to cover on the road in South Carolina.

Diego Pavia and this Commodores offense is rolling, and they can, at the very least, push the Gamecocks to the limit here.

  • Vanderbilt are 9-2-0 ATS in their last 11 games as a betting underdog
  • Vanderbilt are 5-1-0 ATS in their previous 6 road games
  • The Over has hit in 3 of Vanderbilt’s last 4 games against ranked teams

Head To Head

  • South Carolina lead the all-time series 30-4
  • South Carolina won 28-7 when the two teams last met in November 2024

Vanderbilt Form

Vanderbilt head to South Carolina boasting a perfect record thanks to back-to-back wins to start the season.

The Commodores came into 2025 on the back of a memorable 2024 campaign that saw them spring a major upset and run a bunch of ranked teams close.

They stunned #1 Alabama 40-35 in early October, while also losing by just one score to #7 Missouri and #5 Texas.

That meant there were more expectations on Vanderbilt heading into the current season, and they have so far delivered.

The Commodores kicked off the season with a 45-3 blowout of Charleston-Southern, before backing that up with a 44-20 upset of Virginia Tech on the road.

South Carolina Form

South Carolina enter this matchup having opened the 2025 campaign with back-to-back victories, as they look to pick up from where they left off in conference play last season.

The Gamecocks lost three of their first four SEC games in 2024, but rallied to win their final four conference games as part of a six-game run.

That sequence, which included a 17-14 non-conference upset of Clemson, ensured a 9-3 record that earned them a bowl game appearance.

South Carolina have been able to extend their regular-season streak to eight games during the first few weeks of the 2025 season.

The Gamecocks kicked off the campaign with a 24-11 win over Virginia Tech, before downing South Carolina State, 38-10.

Verdict

South Carolina have dominated Vanderbilt in recent years, but this is the best Commodores team they have faced in a long time.

They have started the season strongly and continue to cover both on the road and as an underdog, so give us Vandy and the free points.

Best Bet1: Vanderbilt +5.5 Spread @-111.11 at Stake.us - 4 Units
Best Bet2: Over 48.5 Total Points @-111.11 at Stake.us - 2 Units
Vanderbilt +5.5
Spread
@-111.11 - 4 Units
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Bet at Stake.us
Over 48.5
Total Points
@-111.11 - 2 Units
55 Stake Cash no deposit & 550,000 Gold Coins & 5% Rakeback
Use promo code NEWBONUS

Sign up with the code NEWBONUS. When you verify your account get 25 Stake Cash for free PLUS 250,000 Gold Coins and 5% Rakeback! No deposit required. Login each day for the next 30 days and get an additional 30 Stake Cash AND 300,000 Gold Coins. 21+ only. T&Cs apply. Excludes WA, NY, NV, ID, KY, MI, VT, NJ, DE, WV, PA, RI & MD.

Bet at Stake.us