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Carolina Panthers at Arizona Cardinals Preview & Picks – Cardinals To Take NFL Home Opener

leigh-copson
11 Sep 2025
leigh-copson
Leigh Copson 11 Sep 2025
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  • Carolina Panthers at Arizona Cardinals picks for Sunday, September 14
  • Game is taking place at State Farm Stadium
  • Preview, predictions, stats & form
(Getty Images)
    Carolina Panthers at Arizona Cardinals Preview & Picks
  • Carolina Panthers at Arizona Cardinals Preview & Picks
  • Head To Head
  • Carolina Panthers Form
  • Arizona Cardinals Form

Carolina Panthers at Arizona Cardinals Preview & Picks

Arizona are tipped to cover as they win their home opener.

The Cardinals were efficient as they won on the road a week ago, while Carolina struggled in all areas and turned the ball over repeatedly on offense.

  • Arizona Cardinals are 5-1-0 ATS in their last 6 home games
  • Carolina Panthers are 2-15 in their previous 17 road games
  • Carolina Panthers are 4-14-0 ATS in their last 18 road games
  • The Under cashed in both teams’ season opener

Head To Head

  • Carolina Panthers lead the all-time series 15-6
  • Carolina Panthers won 36-30 in overtime when the two teams last met in December 2024

Carolina Panthers Form

Carolina head out on the road for the second week in a row looking to get their first win of the season.

The Panthers’ playoff drought reached seven seasons in 2024 as they won just five times, and if their 2025 opener is anything to go by, that drought will reach eight seasons.

Bryce Young got the start last Sunday, having been benched and then reinstalled as starting quarterback during the 2024 campaign.

The Carolina QB had a rough day at the offense though as he threw for just 154 yards, with one touchdown and two interceptions.

The Panthers struggled to get anything going on the ground too, and that resulted in a 26-10 defeat at the hands of Jacksonville.

Arizona Cardinals Form

Arizona enter their home opener looking to follow up last weekend’s road win in New Orleans.

The Cardinals suffered their third straight losing season in 2024, but having finished 4-13 in each of the previous two campaigns, their 8-9 record was an improvement.

That record would have been much better had their form not collapsed late in the season, as they lost five of their final seven games to miss out on the postseason.

Arizona did wrap up the campaign on a positive note though, beating San Francisco, and they picked up from where they left off last weekend.

The Cardinals kicked of the 2025 season with a 20-13 victory over the Saints in New Orleans.

Verdict

Arizona may not be a Super Bowl contender, but they are the better team.

The Cardinals enjoyed a winning start last weekend and are expected to make it back-to-back wins at the expense of a Carolina team that has not travelled well for a long time.

Best Bet1: Arizona -6.5 Spread @-111.11 at Stake.us - 4 Units
Best Bet2: Under 43.5 Total Points @-111.11 at Stake.us - 2 Units
Arizona -6.5
Spread
@-111.11 - 4 Units
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Bet at Stake.us
Under 43.5
Total Points
@-111.11 - 2 Units
55 Stake Cash no deposit & 550,000 Gold Coins & 5% Rakeback
Use promo code NEWBONUS

Sign up with the code NEWBONUS. When you verify your account get 25 Stake Cash for free PLUS 250,000 Gold Coins and 5% Rakeback! No deposit required. Login each day for the next 30 days and get an additional 30 Stake Cash AND 300,000 Gold Coins. 21+ only. T&Cs apply. Excludes WA, NY, NV, ID, KY, MI, VT, NJ, DE, WV, PA, RI & MD.

Bet at Stake.us