Betting

Cleveland Browns at Detroit Lions Preview & Picks – Lions To Extend NFL Win Streak

leigh-copson
24 Sep 2025
leigh-copson
Leigh Copson 24 Sep 2025
Share this article
Or copy link
  • Cleveland Browns at Detroit Lions picks for Sunday, September 28
  • Game is taking place at Ford Field
  • Preview, predictions, stats & form
(Getty Images)
    Cleveland Browns at Detroit Lions Preview & Picks
  • Cleveland Browns at Detroit Lions Preview & Picks
  • Head To Head
  • Cleveland Browns Form
  • Detroit Lions Form

Cleveland Browns at Detroit Lions Preview & Picks

Detroit are tipped to cover as they extend their win streak to three games.

The Lions have issued an emphatic response to their season-opening loss and we expect another strong performance at home from Jared Goff & Co.

  • Detroit Lions have won their last 2 games
  • Detroit Lions are 7-2 in their previous 9 home games
  • Cleveland Browns are 1-8-0 ATS in their last 9 road games
  • The Over has cashed in each of Detroit’s last 2 games

Head To Head

  • Detroit Lions lead the all-time series 19-6
  • Cleveland Browns won 13-10 when the two teams last met in November 2021

Cleveland Browns Form

Cleveland head to Detroit looking to build on last weekend’s surprise home win over Green Bay, which got them off the mark.

The Browns won just three games all last season and came into the new campaign aiming to improve on that this time around.

They got off to a rough start though, as they opened the season with back-to-back defeats to division rivals.

Cleveland opened up at home and surrendered a late lead as they were beaten 17-16 by Cincinnati, and that was followed by a 41-17 blowout loss in Baltimore.

The Browns were able to avoid a third straight defeat though, as they rallied in the fourth quarter to beat Green Bay 13-10 thanks to a walk-off field goal.

Detroit Lions Form

Detroit return home on the back of an impressive Monday night win in Baltimore that improved their record to 2-1.

The Lions’ 2024 Super Bowl dream was crushed under the weight of injuries, and insult was added to injury as they then lost two key co-ordinators in the offseason.

That led to plenty of speculation about whether or not there would be a drop-off this season, and a 27-13 defeat in Green Bay on opening weekend only fuelled that discussion.

Detroit have silenced those questions over the past couple of games though, starting with a 52-21 demolition of Chicago.

The Lions then backed that up in Baltimore on Monday night, as they beat the Ravens 38-30.

Verdict

It has been a case of ‘No Ben Johnson, no problem’ for Detroit over the past couple of weeks.

Jared Goff and that offense is firing, and we expect them to crack open a tough Cleveland defense to ensure the Lions win and cover the spread.

Best Bet1: Detroit -8.5 Spread @-111.11 at Stake.us - 4 Units
Best Bet2: Over 44.5 Total Points @-111.11 at Stake.us - 2 Units
Detroit -8.5
Spread
@-111.11 - 4 Units
55 Stake Cash no deposit & 550,000 Gold Coins & 5% Rakeback
Use promo code NEWBONUS

Sign up with the code NEWBONUS. When you verify your account get 25 Stake Cash for free PLUS 250,000 Gold Coins and 5% Rakeback! No deposit required. Login each day for the next 30 days and get an additional 30 Stake Cash AND 300,000 Gold Coins. 21+ only. T&Cs apply. Excludes WA, NY, NV, ID, KY, MI, VT, NJ, DE, WV, PA, RI & MD.

Bet at Stake.us
Over 44.5
Total Points
@-111.11 - 2 Units
55 Stake Cash no deposit & 550,000 Gold Coins & 5% Rakeback
Use promo code NEWBONUS

Sign up with the code NEWBONUS. When you verify your account get 25 Stake Cash for free PLUS 250,000 Gold Coins and 5% Rakeback! No deposit required. Login each day for the next 30 days and get an additional 30 Stake Cash AND 300,000 Gold Coins. 21+ only. T&Cs apply. Excludes WA, NY, NV, ID, KY, MI, VT, NJ, DE, WV, PA, RI & MD.

Bet at Stake.us