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Indianapolis Colts at Pittsburgh Steelers Preview & Picks – Colts’ Stampede To Continue In NFL

leigh-copson
28 Oct 2025
leigh-copson
Leigh Copson 28 Oct 2025
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  • Indianapolis Colts at Pittsburgh Steelers picks for Sunday, November 2
  • Game is taking place at Acrisure Stadium
  • Preview, predictions, stats & form
(Getty Images)
    Indianapolis Colts at Pittsburgh Steelers Preview & Picks
  • Indianapolis Colts at Pittsburgh Steelers Preview & Picks
  • Head To Head
  • Indianapolis Colts Form
  • Pittsburgh Steelers Form

Indianapolis Colts at Pittsburgh Steelers Preview & Picks

Indianapolis are tipped to cover as they win their fifth straight game.

This balanced Colts offense can make the Steelers pick their ‘poison’, while the defense makes timely stops and forces a takeaway or two.

  • Indianapolis Colts have a league-best 7-1 record
  • Indianapolis Colts are 6-1-0 ATS in their 7 victories
  • Pittsburgh Steelers are 0-3-0 ATS in their 3 defeats
  • The Over has cashed in 5 of Indianapolis’ last 6 games

Head To Head

  • Pittsburgh Steelers lead the all-time series 26-8
  • Indianapolis Colts won 27-24 when the two teams last met in September 2024

Indianapolis Colts Form

Indianapolis head to Pittsburgh riding a four-game win streak that has taken them to a league-best 7-1 record.

The Colts opened the season with back-to-back home wins, beating Miami 33-8 and Denver 29-28, before heading to Tennessee to down the Titans, 41-20.

Their perfect start was then halted by a 27-20 loss at the Los Angeles Rams, but the response has been strong.

Indianapolis rebounded with a 40-6 demolition of Las Vegas, and then made it back-to-back wins as they edged Arizona 31-27.

The Colts made it three-in-a-row with a 38-24 success at the Los Angeles Chargers, before making it four straight wins last Sunday as they downed Tennessee at home, 38-14.

Pittsburgh Steelers Form

Pittsburgh enter this matchup looking to snap a two-game losing sequence that has dropped them to 4-3.

The Steelers enjoyed a winning start to the Aaron Rodgers era as they beat his former club, the New York Jets, 34-32 on the road on opening weekend.

They failed to follow that up as they lost the home opener to Seattle, 31-27, but they did rally with a 21-14 victory at New England a week later.

Pittsburgh then backend that up with a 24-21 win over Minnesota in Ireland, before returning home for a 23-9 victory over division rivals Cleveland.

The Steelers’ run was halted in shocking fashion, as they fell 33-31 at Cincinnati, and that was followed by a 35-25 loss at home to Green Bay last time out.

Verdict

Indianapolis are the hottest team in the NFL and are showing no signs of cooling off.

The same cannot be said for Pittsburgh after a couple of rough losses, so we are backing the Colts to come away with the ‘W’.

Best Bet1: Indianapolis -3.0 Spread @-111.11 at Stake.us - 4 Units
Best Bet2: Over 50.5 Total Points @-111.11 at Stake.us - 2 Units
Indianapolis -3.0
Spread
@-111.11 - 4 Units
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Bet at Stake.us
Over 50.5
Total Points
@-111.11 - 2 Units
55 Stake Cash no deposit & 550,000 Gold Coins & 5% Rakeback
Use promo code NEWBONUS

Sign up with the code NEWBONUS. When you verify your account get 25 Stake Cash for free PLUS 250,000 Gold Coins and 5% Rakeback! No deposit required. Login each day for the next 30 days and get an additional 30 Stake Cash AND 300,000 Gold Coins. 21+ only. T&Cs apply. Excludes WA, NY, NV, ID, KY, MI, VT, NJ, DE, WV, PA, RI & MD.

Bet at Stake.us