New England Patriots at Miami Dolphins Preview & Picks – Pats To Add To Miami Misery In NFL
10 Sep 2025
Read More
Los Angeles Rams at San Francisco 49ers Preview & Picks – LA Rams To Cover As Monday NFL Underdog
- Los Angeles Rams at San Francisco 49ers picks for Monday, October 3
- Matchup gets underway at 20:15 ET at Levi's Stadium
- Preview, stats & head-to-head

- Los Angeles Rams at San Francisco 49ers Preview & Picks
- Head To Head
- Los Angeles Rams Form
- San Francisco 49ers Form
- Los Angeles Rams at San Francisco 49ers FAQs
Los Angeles Rams at San Francisco 49ers Preview & Picks
Los Angeles Rams at San Francisco 49ers Preview & Picks
Los Angeles are backed to at least cover as a road underdog.
The Rams have underwhelmed so far, but there is still plenty of talent on both sides of the football.
Improvement is expected in the coming weeks and that cannot be said for San Francisco’s offense.
They are struggling to put up points so the Rams may not need many against this tough 49ers defense.
- LA Rams are 2-0 in their last two games
- LA Rams are 3-1-0 ATS in their last 4 games as a betting underdog
- LA Rams are averaging 4.6 points per game more than San Francisco
- San Francisco have the 4th worst points per game average in the NFL
- The Under has cashed in 10 of San Francisco’s last 11 games
- The Under has cashed in 11 of LA Ram’s last 16 division games
Head To Head
- San Francisco 49ers lead the all-time series 75-68-3
- Los Angeles Rams won 2017 when the teams last met in January 2022
Los Angeles Rams Form
Los Angeles head to Santa Clara looking to win their third consecutive game and knock off a division rival.
The defending Super Bowl champion Rams kicked off the season with a 31-10 home defeat to Buffalo.
They have rebounded though, following up a 31-27 win against Atlanta with a 20-12 victory at Arizona.
QB Matthew Stafford, who is dealing with an elbow injury, has gone 74/102 for 761 yards, four touchdowns and five interceptions.
Cooper Kupp is the team’s leading receiver with 280 yards and three TDs off 28 receptions.
Tyler Higbee has contributed 171 receiving yards, while offseason acquisition Allen Robinson has managed only 88 yards and a score through three games.
Out of the backfield, Cam Akers and Darrell Henderson have combined for 216 yards and two TDs.
On the opposite side of the football, the defense has failed to reach the heights of last season.
They have allowed 23.3 points and 346.3 yards per game to rank in the bottom half of the league.
Los Angeles have averaged 2.3 per game though – the second best takeaway rate in the NFL.
San Francisco 49ers Form
San Francisco head into this Monday Night Football with a 1-2 record following another miserable loss.
The 49ers suffered a shock 19-10 defeat at Chicago on opening weekend, but bounced back to beat Seattle 27-7 in their home opener.
They failed to follow that up though, suffering a miserable 11-10 defeat at Denver in Week 3.
QB Jimmy Garoppolo has replaced the injured Trey Lance as starting QB and has so far gone 31/50 for 365 yards, two touchdowns and a pick.
Brandon Aiyuk is the team’s leading receiver with 142 yards and a TD, while Jeff Wilson has rushed for a team-leading 181 yards.
The biggest weapon on this offense is Deebo Samuel, who has 242 yards from scrimmage and only one TD.
While the offense has faltered, the defense have done their best to keep San Francisco in games.
The 49ers rank third in the league in points per game, giving up just 12.3, but it should be noted that they have faced some of the NFL’s worst offenses.
They are second in yards allowed per game (227.0) and are just outside the top 10 in takeaways per game (1.3).
Los Angeles Rams at San Francisco 49ers FAQs
Where can I watch the Los Angeles Rams at San Francisco 49ers live stream?
You can watch the Los Angeles Rams at San Francisco 49ers live stream at Stake.
What is the Los Angeles Rams at San Francisco 49ers start time?
The Los Angeles Rams at San Francisco 49ers game is set to start at 20:15 ET.
Verdict
Los Angeles are yet to reach the heights of last season.
They appear to be in a better place than San Francisco though, so we are backing the Rams on the road.
They appear to be in a better place than San Francisco though, so we are backing the Rams on the road.
25 SC no deposit & 250,000 GC
Use promo code NEWBONUS
Get 25 Stake Cash & 250,000 Gold Coins when you sign up with code NEWBONUS at Stake.us. USA only. Excludes certain States including NY,NV,ID, KY,WA. 18+ only. Terms and Conditions apply.
25 SC no deposit & 250,000 GC
Use promo code NEWBONUS
Get 25 Stake Cash & 250,000 Gold Coins when you sign up with code NEWBONUS at Stake.us. USA only. Excludes certain States including NY,NV,ID, KY,WA. 18+ only. Terms and Conditions apply.
See also
- NFL 3rd Quarter Pay-Out – Get Paid Out If Your Team Leads By 7+ Points After Three Quarters
- Los Angeles Rams at San Francisco 49ers – Get Double Winnings With Stake’s NFL Primetime Offer
- Los Angeles Rams at San Francisco 49ers Live Stream – How To Watch Live Online With Stake
- Kansas City Chiefs at Tampa Bay Buccaneers Live Stream – How To Watch Live Online With Stake
- Kansas City Chiefs at Tampa Bay Buccaneers Preview & Picks – Under Tipped For Sunday NFL Clash
- NFL Live Stream – How To Watch Every NFL Game Live Online
- Denver Broncos at Las Vegas Raiders Preview & Picks – Raiders To Get Off The Mark
- Jacksonville Jaguars at Philadelphia Eagles Preview & Picks – Jacksonville To Cover As Underdog
- Minnesota Vikings at New Orleans Saints Preview & Picks – Vikings To Cover In NFL London Game
Latest News
-
Patriots Cover
-
Cowboys CoverNew York Giants at Dallas Cowboys Preview & Picks – Cowboys To Cruise To NFL Win10 Sep 2025 Read More
-
Detroit CoverChicago Bears at Detroit Lions Preview & Picks – Lions To Get Off Mark In NFL10 Sep 2025 Read More
-
Arizona CoverCarolina Panthers at Arizona Cardinals Preview & Picks – Cardinals To Take NFL Home Opener11 Sep 2025 Read More
-
Broncos WinDenver Broncos at Indianapolis Colts Preview & Picks – Broncos To Ride Run Game & Defense To NFL Win11 Sep 2025 Read More