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Boston Red Sox at Cleveland Guardians Predictions & Picks – Guardians To Win MLB Series Opener
- Boston Red Sox at Cleveland Guardians picks for Friday, May 29
- Game is taking place at Progressive Field
- Preview, predictions, stats & form
(Getty Images)
- Boston Red Sox at Cleveland Guardians Predictions & Picks
- Head To Head
- Boston Red Sox Form
- Cleveland Guardians Form
- Starting Pitchers
Boston Red Sox at Cleveland Guardians Predictions & Picks
Boston Red Sox at Cleveland Guardians Predictions & Picks
Cleveland are tipped to take the opening game of this home series.
Starter Slade Ceccioni has had his issues this season, but he has been solid at home despite one rough outing, and the Guardians are the team in better form.
- Cleveland Guardians are 12-4 in their last 16 games
- Cleveland have won 4 of the last 5 games Slade Ceccioni appeared in
- Boston Red Sox are 1-5 in their previous 6 games
- The Under has been cashed in 6 of Cleveland’s last 8 games
Head To Head
- Cleveland Guardians lead the all-time series 1074-1013-8
- Cleveland Guardians won 8-1 when the two teams last met in September 2025
Boston Red Sox Form
Boston head to Cleveland on the back of a rough run at home that saw them lose five times in six games.
| Date | Opposition | W/L | Score |
|---|---|---|---|
| May-17 | at Atlanta Braves | L | 1-8 |
| May-18 | at Kansas City Royals | W | 3-1 |
| May-19 | at Kansas City Royals | W | 7-1 |
| May-20 | at Kansas City Royals | W | 4-3 |
| May-22 | vs Minnesota Twins | L | 6-8 |
| May-23 | vs Minnesota Twins | L | 2-4 |
| May-24 | vs Minnesota Twins | L | 5-6 |
| May-26 | vs Atlanta Braves | L | 6-7 |
| May-27 | vs Atlanta Braves | W | 8-0 |
| May-28 | vs Atlanta Braves | L | 2-10 |
Cleveland Guardians Form
Cleveland enter this series having bounced back from a couple of defeats with their 12th victory in their last 16 games.
| Date | Opposition | W/L | Score |
|---|---|---|---|
| May-18 | at Detroit Tigers | W | 8-2 |
| May-19 | at Detroit Tigers | W | 4-3 |
| May-20 | at Detroit Tigers | W | 3-2 |
| May-21 | at Detroit Tigers | W | 3-1 |
| May-22 | at Philadelphia Phillies | W | 1-0 |
| May-23 | at Philadelphia Phillies | L | 0-3 |
| May-24 | at Philadelphia Phillies | W | 3-1 |
| May-25 | vs Washington Nationals | L | 2-10 |
| May-26 | vs Washington Nationals | L | 3-6 |
| May-27 | vs Washington Nationals | W | 3-2 |
Starting Pitchers
| Name | Team | Record | ERA | Strikeouts | Innings |
|---|---|---|---|---|---|
| Tyler Samaniego | Boston Red Sox | 0-2 | 1.04 | 13 | 17.1 |
| Slade Cecconi | Cleveland Guardians | 3-5 | 5.18 | 47 | 57.1 |
Verdict
Slade Ceccioni’s numbers do not make for great reading, but he has delivered strong performances in two of his three home outings this season.
Cleveland’s form has been strong too despite a couple of recent defeats, so we are backing the Guardians here.
Cleveland’s form has been strong too despite a couple of recent defeats, so we are backing the Guardians here.
Cleveland Win
Moneyline
@-120.48 - 4 Units
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