Indiana at Purdue Preview & Picks – Hoosiers To Blow Out Boilermakers In College Football

leigh-copson
24 Nov 2025
Leigh Copson 24 Nov 2025
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  • Indiana at Purdue picks for Friday, November 28
  • Game is taking place at Ross–Ade Stadium
  • Preview, predictions, stats & form
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    Indiana at Purdue Preview & Picks
  • Indiana at Purdue Preview & Picks
  • Head To Head
  • Indiana Form
  • Purdue Form

Indiana at Purdue Preview & Picks

Indiana are tipped to cover the spread as they blow out Purdue on the road.

The unbeaten Hoosiers have played outstanding football this season, while the Boilermakers continue to stack up losses and have rarely covered.

  • Indiana have won all 11 of their games so far
  • Indiana beat Purdue by 66 points last season
  • Purdue are 2-5-1 ATS in their last 8 games
  • The Under has cashed in 8 of Indiana’s 11 games

Head To Head

  • Purdue lead the all-time series 77-43-6
  • Indiana won 66-0 when the two teams last met in November 2024

Indiana Form

Indiana enter their final game of the regular season boasting a 100% record to stay on course for the Big Ten Championship and the playoffs.

The Hoosiers reeled off three non-conference wins to start the season, and then made a statement in their Big Ten opener as they crushed a top-10 ranked Illinois team, 63-10.

They backed that up with a 20-15 win in Iowa, and then recorded their best win of the season so far as they travelled to Oregon and beat the number three-ranked Ducks, 30-20.

Indiana then returned home to win back-to-back games, beating Michigan State 38-13 and UCLA 56-6, before heading back out on the road to down Maryland 55-10 and Penn State 27-24.

The Hoosiers then made it 11-in-a-row last weekend as they beat Wisconsin at home, 31-7.

Purdue Form

Purdue go into their final game of the campaign having lost nine consecutive games to fall to 2-9.

The Boilermakers kicked off the campaign by beating Ball State 31-0 and Southern Illinois 34-17, but it has been all downhill since then.

They began their Big Ten slate with a 33-17 defeat to USC, and then suffered a 56-30 loss to Notre Dame before returning to conference duty to lose 43-27 to Illinois.

Purdue then dropped back-to-back games on the road, losing 27-20 at Minnesota and 19-0 at Northwestern, before heading back home for a 27-24 loss to Rutgers.

The Boilermakers then saw their skid reach nine games as they sandwiched a 34-10 home loss to Ohio State with road defeats to Michigan, 21-16, and Washington, 49-13.

Verdict

Only a catastrophic loss to Purdue can derail Indiana, and we are not expecting that to happen here.

This matchup might not be a repeat of last season’s 66-0 demolition, but we are backing the Hoosiers for a commanding win.

Best Bet1: Indiana -28.5 Spread @-111.11 at Stake.us - 4 Units
Best Bet2: Under 53.5 Total Points @-111.11 at Stake.us - 2 Units
Indiana -28.5
Spread
@-111.11 - 4 Units
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Bet at Stake.us
Under 53.5
Total Points
@-111.11 - 2 Units
55 Stake Cash no deposit & 550,000 Gold Coins & 5% Rakeback
Use promo code NEWBONUS

Sign up with the code NEWBONUS. When you verify your account get 25 Stake Cash for free PLUS 250,000 Gold Coins and 5% Rakeback! No deposit required. Login each day for the next 30 days and get an additional 30 Stake Cash AND 300,000 Gold Coins. 21+ only. T&Cs apply. Excludes WA, NY, NV, ID, KY, MI, VT, NJ, DE, WV, PA, RI & MD.

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