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Ohio State at Illinois Preview & Picks – Back Buckeyes To Cover In College Football Win

leigh-copson
07 Oct 2025
leigh-copson
Leigh Copson 07 Oct 2025
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  • Ohio State at illinois picks for Saturday, October 11
  • Game is taking place at Memorial Stadium
  • Preview, predictions, stats & form
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    Ohio State at Illinois Preview & Picks
  • Ohio State at Illinois Preview & Picks
  • Head To Head
  • Ohio State Form
  • Illinois Form

Ohio State at Illinois Preview & Picks

Ohio State are tipped to cover as they maintain their perfect record.

Buckeyes quarterback Julian Sayin can dissect this Illinois secondary, while that defense locks down yet another opponent to secure the cover.

  • Ohio State are 5-0 so far this season
  • Ohio State are 4-1-0 ATS  through 5 games
  • Illinois are 0-1-0 ATS in defeat this season
  • The Under has cashed in 3 of Ohio State’s first 5 games

Head To Head

  • Ohio State lead the all-time series 18-8
  • Ohio State won 52-14 when the two teams last met in November 2017

Ohio State Form

Ohio State head out on the road for the second time this season looking to maintain a 100% record that has put them top of the AP rankings.

Despite being the defending champions, the Buckeyes entered this season as the number three ranked team in the minds of AP.

They sent a message in their season opener, as they earned a 14-7 victory over a Texas team that had been considered favourites for the national championship this time around.

Ohio State backed that up with a 70-0 shutout of Grambling State, before then downing Ohio 27-9 in a battle of state rivals.

The Buckeyes made it four-in-a-row as they won their Big Ten opener in Washington, 24-6, and then took their perfect start to five games with a 42-3 blowout of Minnesota last weekend.

Illinois Form

Illinois enter the biggest test of their season so far having responded from the embarrassing loss to Indiana with back-to-back wins.

The Fighting Illini opened up with three non-conference games, and backed up 52-3 blowout of Western Illinois with a 45-19 victory at Duke and a 38-0 shutout of Western Michigan at home.

That set them up for their Big Ten opener in Indiana, but they endured a nightmare start to their conference campaign as they were blasted 63-10.

Illinois have rallied over the past couple of weekends though, winning consecutive games to get back on track.

The Fighting Illini responded to that heavy loss with a 34-32 win over USC, before heading out on the road to down Purdue last weekend, 43-27.

Verdict

Ohio State have combined efficient offense with dominant defense to make a 5-0 start.

It is tough to see Illinois hanging many points on a unit that has allowed just five points per game so far, so we expect the Buckeyes to deliver against the spread.

Best Bet1: Ohio State -14.5 Spread @-111.11 at Stake.us - 4 Units
Best Bet2: Under 50.5 Total Points @-111.11 at Stake.us - 2 Units
Ohio State -14.5
Spread
@-111.11 - 4 Units
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Bet at Stake.us
Under 50.5
Total Points
@-111.11 - 2 Units
55 Stake Cash no deposit & 550,000 Gold Coins & 5% Rakeback
Use promo code NEWBONUS

Sign up with the code NEWBONUS. When you verify your account get 25 Stake Cash for free PLUS 250,000 Gold Coins and 5% Rakeback! No deposit required. Login each day for the next 30 days and get an additional 30 Stake Cash AND 300,000 Gold Coins. 21+ only. T&Cs apply. Excludes WA, NY, NV, ID, KY, MI, VT, NJ, DE, WV, PA, RI & MD.

Bet at Stake.us