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Detroit Lions at Green Bay Packers Preview & Picks – Lions To Down Division Rivals In NFL Week 1

leigh-copson
25 Jul 2025
leigh-copson
Leigh Copson 25 Jul 2025
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  • Detroit Lions at Green Bay Packers picks for Sunday, September 7
  • Game is taking place at Lambeau Field in Green Bay
  • Preview, predictions, stats & form
(Getty Images)
    Detroit Lions at Green Bay Packers Preview & Picks
  • Detroit Lions at Green Bay Packers Preview & Picks
  • Head To Head
  • Detroit Lions Form
  • Green Bay Packers Form

Detroit Lions at Green Bay Packers Preview & Picks

Detroit are tipped to win this big NFC North matchup on opening weekend.

Losing their key two co-ordinators is a blow, but the Lions’ roster is loaded with talent and this strong defense can slow down what could be a short-handed Packers offense.

  • Detroit Lions are 6-1 in the last 7 meetings
  • Detroit Lions are 3-0 in their previous 3 visits to Lambeau Field
  • Detroit Lions were 8-0 on the road last season
  • The Under has cashed in 2 of the last 3 meetings at Lambeau Field

Head To Head

  • Green Bay Packers lead the all-time series 106-78-7
  • Detroit Lions won 34-31 when the two teams last met in December 2024

Detroit Lions Form

Detroit enter the new campaign looking to bounce back from a disappointing end to the 2024 season that saw them crash out of the playoffs and lose their two co-ordinators.

The Lions made it all the way to the NFC Championship Game in 2023, so hopes were high that the franchise could finally end their Super Bowl drought last season.

They enjoyed an outstanding regular season that saw them win 15 of their 17 games and go a perfect 6-0 in the division.

However, Detroit’s Super Bowl quest was derailed by injuries and their playoff run proved to be short.

Having earned a bye for Wild card weekend, the Lions’ season was brought to a shuddering halt as they lost 45-31 at home to Washington in the Division round. 

Green Bay Packers Form

Green Bay also come into the 2025 campaign with their sights set on challenging for the Super Bowl.

The Packers endured a rough run in the NFC North last year as they lost all but one of their division games, but that did not cost them a playoff pace.

They advanced to the postseason with an 11-6 record, only to enter the playoffs in poor form following back-to-back defeats to close out the regular season.

Green Bay were beaten 27-25 on the road in Minnesota, before giving up a last-gasp field goal to lose 24-22 at home to Chicago.

The Packers’ losing skid then reached three games as their season was ended by a 22-10 defeat in Philadelphia in the Wild card round.

Verdict

It is tough to ignore Detroit’s recent record against Green Bay, both overall and especially at Lambeau.

The Lions have repeatedly got the better of the Packers and they return with a stacked roster, so give us the visitors in the underdog role.

Best Bet1: Detroit Win Moneyline @100.00 at Stake.us - 4 Units
Best Bet2: Under 49.5 Total Points @-111.11 at Stake.us - 2 Units
Detroit Win
Moneyline
@100.00 - 4 Units
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Bet at Stake.us
Under 49.5
Total Points
@-111.11 - 2 Units
55 Stake Cash no deposit & 550,000 Gold Coins & 5% Rakeback
Use promo code NEWBONUS

Sign up with the code NEWBONUS. When you verify your account get 25 Stake Cash for free PLUS 250,000 Gold Coins and 5% Rakeback! No deposit required. Login each day for the next 30 days and get an additional 30 Stake Cash AND 300,000 Gold Coins. 21+ only. T&Cs apply. Excludes WA, NY, NV, ID, KY, MI, VT, NJ, DE, WV, PA, RI & MD.

Bet at Stake.us