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Los Angeles Rams at Arizona Cardinals Preview & Picks – Rams To Rebound In NFL

leigh-copson
04 Dec 2025
leigh-copson
Leigh Copson 04 Dec 2025
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  • Los Angeles Rams at Arizona Cardinals picks for Sunday, December 7
  • Game is taking place at State Farm Stadium
  • Preview, predictions, stats & form
(Getty Images)

Los Angeles Rams at Arizona Cardinals Preview & Picks

Los Angeles are tipped to cover as they get back to winning ways.

The Rams’ run was ended last time out, but this is still one of the very best teams in the NFC while Arizona have lost nine of the last 10 and are merely playing out their schedule.

  • Los Angeles Rams are 6-1 in their last 7 games
  • Los Angeles Rams are 4-2-0 ATS in their 6 road games
  • Arizona Cardinals are 1-3-0 ATS in their last 4 defeats
  • The Over has cashed in 4 of Los Angeles’ 6 road games

Head To Head

  • Los Angeles Rams lead the all-time series 53-41-2
  • Los Angeles Rams won 13-9 when the two teams last met in December 2024

Los Angeles Rams Form

Los Angeles head to Arizona looking to rebound from a road defeat that ended their recent win streak at six games.

The Rams opened the season with back-to-back wins, beating Houston 14-9 and Tennessee 33-19, but failed to make it three-in-a-row as they lost 33-26 in Philadelphia.

They rebounded to beat Indianapolis at home, 27-20, only to then suffer a 27-23 overtime defeat when they entertained division rivals San Francisco.

Los Angeles rebounded strongly though, beating Baltimore 17-3 and Jacksonville 35-7 on the road, and then backed up a 34-10 home win against New Orleans with a 42-26 victory at San Francisco.

The Rams made it six straight as they returned home to down Seattle 21-19 and Tampa Bay 34-7, but they were unable to make it seven-in-a-row as they fell 31-28 in Carolina.

Arizona Cardinals Form

Arizona enter this matchup having lost nine of their previous 10 games and each of the last four.

The Cardinals kicked off the campaign with back-to-back wins, beating New Orleans 20-13 and Carolina 27-22, but their form nose-dived after that.

Their perfect start was ended by a 16-15 loss at San Francisco, and they then lost 23-20 to Seattle and 22-21 to Tennessee at home, before falling 31-27 in Indianapolis.

Arizona then lost 27-23 at home to Green Bay, and although they finally stopped the rot with a 27-17 upset of Dallas on the road, they were unable to back that up.

The Cardinals followed up a 44-22 defeat in Seattle with a 41-22 loss to San Francisco, a 27-24 overtime defeat to Jacksonville and a 20-17 defeat at Tampa Bay.

Verdict

Los Angeles lost last time out, but it is tough to imagine that will become back-to-back defeats here.

Arizona are already looking to 2026, so we are backing the Rams to cover the spread as they return to winning ways.

Best Bet1: LA Rams -8.0 Spread @-111.11 at Stake.us - 4 Units
Best Bet2: Over 48.5 Total Points @-111.11 at Stake.us - 2 Units
LA Rams -8.0
Spread
@-111.11 - 4 Units
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Bet at Stake.us
Over 48.5
Total Points
@-111.11 - 2 Units
55 Stake Cash no deposit & 550,000 Gold Coins & 5% Rakeback
Use promo code NEWBONUS

Sign up with the code NEWBONUS. When you verify your account get 25 Stake Cash for free PLUS 250,000 Gold Coins and 5% Rakeback! No deposit required. Login each day for the next 30 days and get an additional 30 Stake Cash AND 300,000 Gold Coins. 21+ only. T&Cs apply. Excludes WA, NY, NV, ID, KY, MI, VT, NJ, DE, WV, PA, RI & MD.

Bet at Stake.us