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Miami Dolphins at Buffalo Bills Preview & Picks – Bills To Down Dolphins In NFL Thursday Matchup

leigh-copson
15 Sep 2025
leigh-copson
Leigh Copson 15 Sep 2025
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  • Miami Dolphins at Buffalo Bills picks for Thursday, September 18
  • Game is taking place at Highmark Stadium
  • Preview, predictions, stats & form
(Getty Images)
    Miami Dolphins at Buffalo Bills Preview & Picks
  • Miami Dolphins at Buffalo Bills Preview & Picks
  • Head To Head
  • Miami Dolphins Form
  • Buffalo Bills Form

Miami Dolphins at Buffalo Bills Preview & Picks

Buffalo are tipped to maintain their perfect record with a win over their division rivals.

The Bills are firing on all cylinders and Josh Allen can light up this bad Dolphins defense to ensure the double digit cover.

  • Buffalo Bills are 2-0-0 ATS so far this season
  • Miami Dolphins are 0-2-0 ATS through their first 2 games
  • Buffalo Bills are 9-1 in the previous 10 meetings with Miami
  • The Over has cashed in 3 of the previous 4 meetings

Head To Head

  • Miami Dolphins lead the all-time series 62-60-1
  • Buffalo Bills won 30-27 when the two teams last met in November 2024

Miami Dolphins Form

Miami head out on the road in desperate need of a victory, having opened with back-to-back defeats.

Dolphins head coach Mike McDaniel came into the new season on a hot seat after a disappointing 2024 campaign that saw the team finish 8-9 to miss out on the playoffs.

And with two 2025 outings now in the books, McDaniel’s seat has got even hotter heading into this short week.

Miami kicked off the season on the road and managed just eight points in a 33-8 blowout defeat to the Colts in Indianapolis.

The Dolphins then failed to rebound from that loss in their home opener, as they were beaten 33-27 by New England to fall to 0-2.

Buffalo Bills Form

Buffalo return home boasting a 100% record as they look to finally get their hands on the Vince Lombardi Trophy this season.

The Bills have been a leading contender for Super Bowl over the past several seasons, but every year they have come up painfully short at the business end of the campaign.

Josh Allen & Co. are looking to ensure that is not the case this time around, and they have made a solid start to their quest.

Buffalo appeared to be headed to defeat on opening night, only to produce a sensational late fightback to beat Baltimore 41-40 at home.

The Bills then backed that up last Sunday, as they eased to a 30-10 win at division rivals, the New York Jets.

Verdict

Buffalo have dominated Miami in recent years and that trend is unlikely to end here.

Everything we have seen through the first two weeks of the season suggests the Bills will take this game, and win it comfortably too.

Best Bet1: Buffalo -12.5 Spread @-111.11 at Stake.us - 4 Units
Best Bet2: Over 49.5 Total Points @-111.11 at Stake.us - 2 Units
Buffalo -12.5
Spread
@-111.11 - 4 Units
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Bet at Stake.us
Over 49.5
Total Points
@-111.11 - 2 Units
55 Stake Cash no deposit & 550,000 Gold Coins & 5% Rakeback
Use promo code NEWBONUS

Sign up with the code NEWBONUS. When you verify your account get 25 Stake Cash for free PLUS 250,000 Gold Coins and 5% Rakeback! No deposit required. Login each day for the next 30 days and get an additional 30 Stake Cash AND 300,000 Gold Coins. 21+ only. T&Cs apply. Excludes WA, NY, NV, ID, KY, MI, VT, NJ, DE, WV, PA, RI & MD.

Bet at Stake.us