Miami FL vs Indiana Preview & Picks – Canes To Cover As National Championship Underdog
12 Jan 2026Read More
LSU vs USC Preview & Picks – LSU To Win College Football’s Vegas Kickoff Classic
- LSU vs USC picks for Sunday, September 1
- Game is taking place at Allegiant Stadium in Las Vegas
- Preview, predictions, stats & form
(Getty Images)
- LSU vs USC Preview & Picks
- Head To Head
- LSU Form
- USC Form
LSU vs USC Preview & Picks
LSU vs USC Preview & Picks
LSU are tipped to cover the spread as the win this season opener.
Both teams lost their starting QB to the NFL, but USC face the bigger task replacing Caleb Williams.
They also need to transform a defense that gave up a ton of points during the 2024 campaign.
- LSU are 6-2-0 ATS in their last 8 games
- USC have a 2-6 record in their previous 8 games
- USC are 2-8-0 ATS in their last 10 matchups
- The Over has cashed in 17 of the last 10 games involving either of these teams
Head To Head
- The all-time series is split 1-1
- LSU won 23-3 when the two teams last met in September 1984
LSU Form
LSU enter the 2024 campaign looking to force their way back into the national championship picture.
The Tigers went 10-3 last time around, with defeats in three of their four games against ranked teams proving costly.
They opened with a 45-24 defeat to Florida State, but rebounded with three consecutive victories before falling to another ranked team, Ole Miss, 55-49.
LSU answered with their only win over a ranked team in 2023, beating Missouri 49-39, only to then lose 42-28 when they visited Alabama in early November.
The Tigers responded with three straight wins to wrap up their regular season schedule, and then took their streak to four games with a 35-31 success against Wisconsin in the ReliaQuest Bowl.
USC Form
USC come into the new season looking to improve on a 2023 campaign that saw them go 7-5 in the regular season.
The Trojans’ offense, led by Caleb Williams, repeatedly put up plenty of points, but defensive issues proved to be their undoing during the second half of the season.
They opened up the campaign with a six-game win streak, but saw that run end with a 48-20 defeat at Notre Dame.
That proved to be the start of a run of five defeats win in six games, with USC’s only victory being a 50-49 victory over California.
The Trojans lost to four ranked teams during that sequence, but a 42-28 win over Louisville in the Holiday Bowl meant they managed one victory over a top-25 school in 2023.
Verdict
Both teams have new quarterbacks leading the way so there are question marks surrounding both teams.
However, the biggest question mark surrounds a USC defense that repeatedly got gashed in 2023, so we are leaning towards LSU in this one.
However, the biggest question mark surrounds a USC defense that repeatedly got gashed in 2023, so we are leaning towards LSU in this one.
LSU -6.0
Spread
@-111.11 - 3 Units
55 Stake Cash no deposit & 550,000 Gold Coins & 5% Rakeback
Use promo code NEWBONUS
Sign up with the code NEWBONUS. When you verify your account get 25 Stake Cash for free PLUS 250,000 Gold Coins and 5% Rakeback! No deposit required. Login each day for the next 30 days and get an additional 30 Stake Cash AND 300,000 Gold Coins. 21+ only. T&Cs apply. Excludes WA, NY, NV, ID, KY, MI, VT, NJ, DE, WV, PA, RI & MD.
Over 62.5
Total Points
@-111.11 - 3 Units
55 Stake Cash no deposit & 550,000 Gold Coins & 5% Rakeback
Use promo code NEWBONUS
Sign up with the code NEWBONUS. When you verify your account get 25 Stake Cash for free PLUS 250,000 Gold Coins and 5% Rakeback! No deposit required. Login each day for the next 30 days and get an additional 30 Stake Cash AND 300,000 Gold Coins. 21+ only. T&Cs apply. Excludes WA, NY, NV, ID, KY, MI, VT, NJ, DE, WV, PA, RI & MD.
See also
- Fresno State at Michigan Preview & Picks – Wolverines To Miss Out On Cover In College Football Opener
- Georgia vs Clemson Preview & Picks – Bulldogs To Tame Tigers In College Football Opener
- North Dakota State at Colorado Preview & Picks – Buffaloes To Kick Off College Football Campaign With Victory
- Miami FL at Florida Preview & Picks – Hurricanes To Blow Through Swamp In College Football
- Notre Dame at Texas A&M Preview & Picks – Aggies To Kick Off Elko Era With College Football Win
- Akron at Ohio State Preview & Picks – Buckeyes To Kick Off College Football Campaign With Dominant Win
- Boston College at Florida State Preview & Picks – Eagles To Avoid Blowout In Seminoles College Football Clash
Upcoming Events
07 March 2026
DC United v Inter Miami Soccer
DC United vs Inter Miami Preview & Picks - Lionel Messi To Fire Miami To MLS Win
08 March 2026
Max Holloway vs Charles Oliveira 2 UFC
Max Holloway vs Charles Oliveira 2 Preview & Picks – Holloway To Retain BMF Crown At UFC 326
UFC 326: Holloway vs Oliveira 2 Offer - Money Back If Your Pick Loses In Final Round
UFC 326 Offer – Double Winnings If Your UFC Pick Wins In First 60 Seconds
Max Holloway vs Charles Oliveira 2 Offer – Win Share Of $50,000 Betting On UFC 326
How To Watch UFC 326: Holloway vs Oliveira 2 Live Stream
UFC 326 Prize Pool – $25,000 Up For Grabs For Max Holloway vs Charles Oliveira 2
Max Holloway vs Charles Oliveira 2 UFC
Max Holloway vs Charles Oliveira 2 Preview & Picks – Holloway To Retain BMF Crown At UFC 326
UFC 326: Holloway vs Oliveira 2 Offer - Money Back If Your Pick Loses In Final Round
UFC 326 Offer – Double Winnings If Your UFC Pick Wins In First 60 Seconds
Max Holloway vs Charles Oliveira 2 Offer – Win Share Of $50,000 Betting On UFC 326
How To Watch UFC 326: Holloway vs Oliveira 2 Live Stream
UFC 326 Prize Pool – $25,000 Up For Grabs For Max Holloway vs Charles Oliveira 2
09 March 2026
Jai Opetaia vs Brandon Glanton Boxing
Jai Opetaia vs Brandon Glanton Preview & Picks – Opetaia To Retain IBF Cruiserweight Crown At Zuffa Boxing 04
15 March 2026
Arnold Barboza Jr vs Kenneth Sims Jr Boxing
Arnold Barboza Jr vs Kenneth Sims Jr Live Stream – How To Watch Live Online
20 March 2026
Michael Conlan vs Kevin Walsh Boxing
Michael Conlan vs Kevin Walsh Live Stream – How To Watch Live Online
21 March 2026
George Liddard vs Tyler Denny Boxing
George Liddard vs Tyler Denny Live Stream – How To Watch Live Online
22 March 2026
27 March 2026
2026 MLB World Series Betting Preview Baseball
2026 MLB World Series Odds – LA Dodgers Favourites For 3-Peat
28 March 2026
2026 UFL Betting Preview American Football
2026 UFL Championship Odds – Stallions Backed To Regain Spring American Football Crown
04 April 2026
23 April 2026
17 May 2026
Ronda Rousey vs Gina Carano UFC
Ronda Rousey vs Gina Carano Preview & Picks – Rousey To Tap Out Carano In Netflix Super-Fight
30 June 2026
NHL 2025/26 Betting Specials Ice Hockey
NHL Daily Pick ‘Em Game – Win Cash Prizes, Trips To NHL Games & More With BET99's Free-To-Play Competition
20 September 2026
Floyd Mayweather Jr vs Manny Pacquiao 2 Boxing
Floyd Mayweather Jr vs Manny Pacquiao 2 Preview & Picks – Mayweather To Repeat 2015 Victory
Poker EventsStarts in
DC United v Inter Miami
Max Holloway vs Charles Oliveira 2
Jai Opetaia vs Brandon Glanton
Arnold Barboza Jr vs Kenneth Sims Jr
Michael Conlan vs Kevin Walsh
George Liddard vs Tyler Denny
Carlos Adames vs Austin Williams
2026 MLB World Series Betting Preview
2026 UFL Betting Preview
Moses Itauma vs Jermaine Franklin
Derek Chisora vs Deontay Wilder
2026 NFL Draft
Latest News
-
Hurricanes Cover -
Hoosiers CoverIndiana vs Oregon Preview & Picks – Hoosiers To Repeat Regular Season Success In Peach Bowl05 Jan 2026Read More
-
Canes WinOle Miss vs Miami FL Preview & Picks – Hurricanes To Claim Fiesta Bowl Crown05 Jan 2026Read More
-
Bulldogs CoverGeorgia vs Ole Miss Preview & Picks – Georgia To Cover In Sugar Bowl Victory31 Dec 2025Read More
-
Indiana AdvanceIndiana vs Alabama Preview & Picks – Back Unbeaten Hoosiers For Rose Bowl Cover31 Dec 2025Read More
