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Ohio State at Purdue Preview & Picks – Buckeyes To Blow Out Boilermakers In College Football

leigh-copson
03 Nov 2025
leigh-copson
Leigh Copson 03 Nov 2025
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  • Ohio State at Purdue picks for Saturday, November 8
  • Game is taking place at Ross-Ade Stadium
  • Preview, predictions, stats & form
(Getty Images)
    Ohio State at Purdue Preview & Picks
  • Ohio State at Purdue Preview & Picks
  • Head To Head
  • Ohio State Form
  • Purdue Form

Ohio State at Purdue Preview & Picks

Ohio State are tipped to cover as they make straightforward work of Purdue.

The Buckeyes defense has dominated every opponent this season, while the offense continues to score plenty of points at a consistent clip.

  • Ohio State are 8-0-1 ATS in their 9 games
  • Purdue are 1-5-0 ATS in their last 6 games
  • The Under has cashed in each of Ohio State’s last 3 road games
  • The Under has hit in 7 of Purdue’s 9 games this season

Head To Head

  • Ohio State lead the all-time series 18-5
  • Ohio State won 45-0 when the two teams last met in November 2024

Ohio State Form

Ohio State head out on the road boasting a perfect record, having won all eight of their games this season.

The Buckeyes entered the season as the defending champions, but they were not considered the number one team in the nation by AP.

That all changed in the season opener though, as they downed top-ranked Texas 14-7 to claim top spot.

Ohio State backed that up with non-conference wins over Grambling State, 70-0, and Ohio, 37-9, before kicking off their Big Ten schedule with a 24-6 win at Washington.

The Buckeyes then went on to beat Minnesota 42-3, Illinois 34-16, Wisconsin 34-0 and Penn State 38-14 to reach 8-0 and retain the number one spot in the polls.

Purdue Form

Purdue return home having seen their losing skid reach seven games to leave them with a 2-7 record.

The Boilermakers opened with back-to-back non-conference games, and ran out 31-0 winners against Ball State and 34-17 victors against Southern Illinois.

They failed to maintain that form in their Big Ten opener though, as they fell 33-17 to USC, and a week later they suffered a 56-30 defeat at the hands of Notre Dame.

Purdue then went out on the road to lose 27-20 in Minnesota and 19-8 at Northwestern, before returning home for a 27-24 defeat to Rutgers.

The Boilermakers’ slide then reached seven games last weekend as they were beaten 21-16 at Michigan.

Verdict

Ohio State have been steamrollering over the opposition this season, and that is unlikely to change here.

Purdue do not have the talent to lay a glove on the Buckeyes, so we expect to see something similar to the 45-0 rout we saw when the two teams met last year.

Best Bet1: Ohio State -28.5 Spread @-111.11 at Stake.us - 4 Units
Best Bet2: Under 48.5 Total Points @-111.11 at Stake.us - 2 Units
Ohio State -28.5
Spread
@-111.11 - 4 Units
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Bet at Stake.us
Under 48.5
Total Points
@-111.11 - 2 Units
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Use promo code NEWBONUS

Sign up with the code NEWBONUS. When you verify your account get 25 Stake Cash for free PLUS 250,000 Gold Coins and 5% Rakeback! No deposit required. Login each day for the next 30 days and get an additional 30 Stake Cash AND 300,000 Gold Coins. 21+ only. T&Cs apply. Excludes WA, NY, NV, ID, KY, MI, VT, NJ, DE, WV, PA, RI & MD.

Bet at Stake.us