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Detroit Lions at Kansas City Chiefs Preview & Picks – Lions To Leave Arrowhead With NFL Win

leigh-copson
09 Oct 2025
leigh-copson
Leigh Copson 09 Oct 2025
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  • Detroit Lions at Kansas City Chiefs picks for Sunday, October 12
  • Game is taking place at Arrowhead Stadium
  • Preview, predictions, stats & form
(Getty Images)
    Detroit Lions at Kansas City Chiefs Preview & Picks
  • Detroit Lions at Kansas City Chiefs Preview & Picks
  • Head To Head
  • Detroit Lions Form
  • Kansas City Chiefs Form

Detroit Lions at Kansas City Chiefs Preview & Picks

Detroit are backed to win as an underdog and add to Kansas City’s problems.

The Lions’ offense is delivering on the ground and through the air, and this defense is more than capable of making some key stops to ensure Arrowhead is silenced.

  • Detroit Lions are on a 4-game win streak
  • Kansas City Chiefs are 2-3 so far this season
  • Detroit Lions won when they last visited Arrowhead in 2023
  • The Over has cashed in 3 of Detroit’s previous 4 games

Head To Head

  • Kansas City Chiefs lead the all-time series 9-6
  • Detroit Lions won 21-20 when the two teams last met in September 2023

Detroit Lions Form

Detroit head to Arrowhead having rebounded from their opening-day defeat with four consecutive wins.

The Lions endured a miserable start as they lost 27-13 at division rivals Green Bay, but their response has been strong.

They got off the mark with a 52-21 blowout of NFC North foes Chicago, and backed that up on the road as they downed Baltimore 38-30.

That victory over the Ravens proved to be the start of a successful run for Detroit against teams from the AFC North.

The Lions eased to a 34-10 victory at home to Cleveland, before heading back out on the road for a 37-24 success in Cincinnati.

Kansas City Chiefs Form

Kansas City enter this matchup in desperate need of a morale-boosting win, having slipped to 2-3 last time out.

The Chiefs entered the new campaign looking to regain the Vince Lombardi Trophy they surrendered to Philadelphia, but things have not gone to plan so far.

They opened up with a trip to Brazil, where they suffered a 27-21 defeat at the hands of division rivals, the Los Angeles Chargers.

Kansas City then lost the Super Bowl rematch with Philadelphia at home, 20-17, before finally getting their first win on the board as they beat the New York Giants on the road, 22-9.

The Chiefs made it back-to-back wins as they then downed Baltimore at home, 37-20, but they were unable to make it three-in-a-row as they lost 31-28 in Jacksonville.

Verdict

We are just five weeks into the season and Kansas City have three losses on their record already, but could that really become four?

Detroit have got over their opening-day misfire and have all of the momentum, so give us the Lions and the plus-money on them repeating their 2023 success at Arrowhead.

Best Bet1: Detroit Win Moneyline @110.00 at Stake.us - 4 Units
Best Bet2: Over 52.5 Total Points @-111.11 at Stake.us - 2 Units
Detroit Win
Moneyline
@110.00 - 4 Units
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Bet at Stake.us
Over 52.5
Total Points
@-111.11 - 2 Units
55 Stake Cash no deposit & 550,000 Gold Coins & 5% Rakeback
Use promo code NEWBONUS

Sign up with the code NEWBONUS. When you verify your account get 25 Stake Cash for free PLUS 250,000 Gold Coins and 5% Rakeback! No deposit required. Login each day for the next 30 days and get an additional 30 Stake Cash AND 300,000 Gold Coins. 21+ only. T&Cs apply. Excludes WA, NY, NV, ID, KY, MI, VT, NJ, DE, WV, PA, RI & MD.

Bet at Stake.us