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New England Patriots at Buffalo Bills Preview & Picks – Patriots To Push Bills In Sunday NFL Showdown
- New England Patriots at Buffalo Bills picks for Sunday, October 5
- Game is taking place at Highmark Stadium
- Preview, predictions, stats & form
(Getty Images)
- New England Patriots at Buffalo Bills Preview & Picks
- Head To Head
- New England Patriots Form
- Buffalo Bills Form
New England Patriots at Buffalo Bills Preview & Picks
New England Patriots at Buffalo Bills Preview & Picks
New England are tipped to cover as a betting underdog in Buffalo.
The Bills are the better team, but the Patriots are improving and they have a strong recent spread record against Buffalo despite repeatedly being the underdog.
- Buffalo Bills are 0-2-0 ATS in their last 2 home games
- New England Patriots are 4-0-0 ATS in the previous 4 meetings with Buffalo
- The Over has cashed in 3 of Buffalo’s 4 games
- The Over hit in New England’s previous road game
Head To Head
- New England Patriots lead the all-time series 79-51-1
- New England Patriots won 23-16 when the two teams last met on January 5
New England Patriots Form
New England go into the first of three straight road games having split their first four games of the season.
The Patriots brought back former player Mike Vrabel as head coach in the off-season, and things have looked promising through the first few weeks.
They already halfway towards their win total from last season, having twice issued immediate responses to defeats.
New England lost their season opener at home to Las Vegas, only to rebound with a 33-27 win at division rivals Miami.
The Patriots then suffered a 21-14 home defeat to Pittsburgh, but responded immediately in the form of a 42-13 blowout of Carolina.
Buffalo Bills Form
Buffalo enter this big AFC East matchup boasting a perfect record, having won each of their first four games of the season.
The Bills entered the 2025 campaign as a leading contender to win the Super Bowl, and staged an amazing late fightback to beat Baltimore 41-40 on opening night.
They backed that up a week later as they went out on the road to beat division rivals, the New York Jets, 30-10.
Buffalo then returned home to take down another AFC East opponent, beating Miami 31-21 on Thursday Night Football.
The Bills remained at home for last weekend’s game too, and retained their 100% record with a 31-19 victory over New Orleans.
Verdict
We expect Buffalo to come out on top here, but we are less confident about their chances of covering.
The Patriots have shown early signs of improvement and they have repeatedly covered against the Bills in recent seasons, so give us those free points.
The Patriots have shown early signs of improvement and they have repeatedly covered against the Bills in recent seasons, so give us those free points.
New England +8.5
Spread
@-111.11 - 4 Units
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Over 50.5
Total Points
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