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San Francisco 49ers at Tampa Bay Buccaneers Preview & Picks – Bucs To Beat 49ers In NFL

leigh-copson
4 hours ago
leigh-copson
Leigh Copson 4 hours ago
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  • San Francisco 49ers at Tampa Bay Buccaneers picks for Sunday, October 12
  • Game is taking place at Raymond James Stadium
  • Preview, predictions, stats & form
(Getty Images)
    San Francisco 49ers at Tampa Bay Buccaneers Preview & Picks
  • San Francisco 49ers at Tampa Bay Buccaneers Preview & Picks
  • Head To Head
  • San Francisco 49ers Form
  • Tampa Bay Buccaneers Form

San Francisco 49ers at Tampa Bay Buccaneers Preview & Picks

Tampa Bay are tipped to cover as they improve their record to 5-1.

Baker Mayfield is balling out for the Bucks, whose offensive firepower can see them past a 49ers team that is dealing with a bunch of injuries.

  • Tampa Bay Buccaneers are 4-1 so far this season
  • Tampa Bay Buccaneers are 2-0-0 ATS against San Francisco in each of the past 2 seasons
  • The Over has hit in 3 of San Francisco’s last 4 games
  • The Over has cashed in each of Tampa Bay’s last 3 games

Head To Head

  • San Francisco 49ers lead the all-time series 21-7
  • San Francisco 49ers won 23-20 when the two teams last met in November 2024

San Francisco 49ers Form

San Francisco make the long trip to Tampa having bounced back from their first defeat of the season to improve to 4-1.

The 49ers opened up the season with back-to-back road games, but that did not prevent them from making a flying start.

They first beat division rivals Seattle 17-13, and then backed that up with a 26-21 success against the Saints in New Orleans.

San Francisco made it three-in-a-row as they won their home opener against Arizona, 16-15, only to see that run end as they were beaten 26-21 by Jacksonville at home.

The 49ers issued an immediate response though, as they won on the road against division rivals, the Los Angeles Rams, 26-23 in overtime.

Tampa Bay Buccaneers Form

Tampa Bay also enter this matchup having rebounded from a first loss to take their record to 4-1.

And just like their opponents on Sunday, the Buccaneers also made a fine start with back-to-back road victories.

They opened with a 23-20 win over the Falcons in Atlanta, and followed that up with a 20-19 victory when they visited Houston.

Tampa Bay made it three-in-a-row by beating the New York Jets in their home opener, 29-27, but their perfect start finally ended a week later as they lost 31-25 to Philadelphia.

The Buccaneers bounced back on the road though, as they downed the Seahawks in Seattle, 38-35.

Verdict

San Francisco are finding a way to overcome their injuries, but that is unlikely on this coast-to-coast trip.

The Bucs are rolling with Baker Mayfield at the controls, so we are backing Tampa Bay to cover as they win this.

Best Bet1: Tampa Bay -3.5 Spread @-111.11 at Stake.us - 4 Units
Best Bet2: Over 48.5 Total Points @-111.11 at Stake.us - 2 Units
Tampa Bay -3.5
Spread
@-111.11 - 4 Units
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Bet at Stake.us
Over 48.5
Total Points
@-111.11 - 2 Units
55 Stake Cash no deposit & 550,000 Gold Coins & 5% Rakeback
Use promo code NEWBONUS

Sign up with the code NEWBONUS. When you verify your account get 25 Stake Cash for free PLUS 250,000 Gold Coins and 5% Rakeback! No deposit required. Login each day for the next 30 days and get an additional 30 Stake Cash AND 300,000 Gold Coins. 21+ only. T&Cs apply. Excludes WA, NY, NV, ID, KY, MI, VT, NJ, DE, WV, PA, RI & MD.

Bet at Stake.us