Miami FL vs Indiana Preview & Picks – Canes To Cover As National Championship Underdog
12 Jan 2026Read More
Indiana at Notre Dame Preview & Picks – Fighting Irish To Advance In College Football Playoffs
- Indiana at Notre Dame picks for Friday, December 20
- Playoff First-Round Game is taking place at Notre Dame Stadium
- Preview, predictions, stats & form
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- Indiana at Notre Dame Preview & Picks
- Head To Head
- Indiana Form
- Notre Dame Form
Indiana at Notre Dame Preview & Picks
Indiana at Notre Dame Preview & Picks
Notre Dame are backed to cover as they advance to the quarter-finals of the playoffs.
The shock loss to Northern Illinois is a distant memory for the Fighting Irish, who have been on a dominant run since then and boast home field advantage for this matchup.
- Notre Dame are on a 10-game win streak
- Notre Dame are 10-2-0 ATS this season
- Indiana are 0-1-0 ATS against ranked opposition
- The Over has hit in 16 of the 24 games involving either of these teams
Head To Head
- Notre Dame lead the all-time series 23-5-1
- Notre Dame won 49-27 when these two teams last met in September 1991
Indiana Form
Indiana sealed their place in the College Football Playoffs by winning 11 of their 12 regular season games.
The Hoosiers opened the season with a couple of non-conference wins, before taking down UCLA, 42-13 in their conference opener.
They followed up that victory as they went on to win their first seven Big Ten games, surging into the top 10 in early November as they beat Michigan State 47-10 and Michigan 20-15.
That set up a huge meeting with Ohio State, but Indiana were unable to maintain their perfect record as they lost 38-15, costing them a trip to the conference championship.
The Hoosiers did bounce back in their regular season finale though, shutting out Purdue in a 66-0 victory.
Notre Dame Form
Notre Dame enter the College Football Playoffs having bounced back from a shock defeat in September with 10 straight victories to finish 11-1.
The Fighting Irish opened with a 23-13 victory at Texas A&M, only to suffer a sensational 16-14 defeat when they hosted Northern Illinois in their home opener.
Their response was emphatic though, as they beat Purdue 66-7 to spark a run of 10 consecutive wins that included successes against three ranked teams.
Notre Dame beat Louisville 31-24 at home, before downing both Navy and Army on neutral sites, 51-14 and 49-14 respectively.
The Fighting Irish then wrapped up their regular season campaign with a 49-35 win at USC, ensuring they would make the first ever 12-team playoffs.
Verdict
This should be a great matchup between two good teams, and we give the edge to Notre Dame.
The Fighting Irish have been red-hot over the past couple of months and in Indiana’s only major test of the season so far, they came up short.
The Fighting Irish have been red-hot over the past couple of months and in Indiana’s only major test of the season so far, they came up short.
Notre Dame -7.5
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@-111.11 - 4 Units
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