Buffalo Sabres at Boston Bruins Predictions & Picks – Bruins To Edge Ahead In NHL Playoffs Series

leigh-copson
22 Apr 2026
Leigh Copson 22 Apr 2026
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  • Buffalo Sabres at Boston Bruins picks for Thursday, April 22
  • Game is taking place at TD Garden
  • Preview, predictions stats & form
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Buffalo Sabres at Boston Bruins Predictions & Picks

Boston are tipped to follow up their Game 2 victory with a win on the home ice.

The Bruins have been able to disrupt Buffalo’s offense through two games, and the Sabres have been struggling massively on the power play. 

  • Boston Bruins are 4-2 in the last 6 meetings
  • Boston Bruins won both regular season meetings at home
  • 5 of the last 7 meetings have produced at least 6 goals

Head To Head

  • Boston Bruins lead the all-time series 188-139-43
  • Boston Bruins won 4-2 when the two teams last met on April 21

Buffalo Sabres Form

Buffalo head out on the road on the back of a loss, but in decent form having won five of their previous seven games.

DateOppositionW/LScore
Mar-31 vs New York Islanders W 04-Mar
Apr-02 at Ottawa Senators L 1-4
Apr-04 at Washington Capitals L 2-6
Apr-06 vs Tampa Bay Lightning W 4-2
Apr-08 at New York Rangers W 5-3
Apr-09 vs Columbus Blue Jackets W 5-0
Apr-13 at Chicago Blackhawks W 5-1
Apr-15 vs Dallas Stars L 3-4 SO
Apr-19 vs Boston Bruins W 4-3
Apr-21 vs Boston Bruins L 2-4

Boston Bruins Form

Boston return home having knotted up this series at 1-1 with their third victory in their last four games.

DateOppositionW/LScore
Mar-31 vs Dallas Stars W 6-3
Apr-02 at Florida Panthers L 1-2
Apr-04 at Tampa Bay Lightning L 1-3
Apr-05 at Philadelphia Flyers L 1-2 OT
Apr-07 at Carolina Hurricanes L 5-6 OT
Apr-11 vs Tampa Bay Lightning L 1-2
Apr-12 at Columbus Blue Jackets W 3-2
Apr-14 vs New Jersey Devils W 4-0
Apr-19 at Buffalo Sabres L 3-4
Apr-21 at Buffalo Sabres W 4-2

Verdict

This is shaping up to be a series that goes back-and-forth, and we are leaning towards Boston in Game 3.

The Bruins are 2-0 when hosting Buffalo this season, and they return home in buoyant mood after Tuesday’s road win.

Best Bet1: Boston Win Moneyline @-111.11 at Stake.us - 4 Units
Best Bet2: Over 6.0 Total Goals @-111.11 at Stake.us - 2 Units
Boston Win
Moneyline
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Bet at Stake.us
Over 6.0
Total Goals
@-111.11 - 2 Units
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Use promo code NEWBONUS

Sign up with the code NEWBONUS. When you verify your account get 25 Stake Cash for free PLUS 250,000 Gold Coins and 5% Rakeback! No deposit required. Login each day for the next 30 days and get an additional 30 Stake Cash AND 300,000 Gold Coins. 21+ only. T&Cs apply. Excludes WA, NY, NV, ID, KY, MI, VT, NJ, DE, WV, PA, RI & MD.

Bet at Stake.us

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