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Tampa Bay Buccaneers at Buffalo Bills Preview & Picks – Bucs To Notch Another NFL Road Cover

leigh-copson
By Leigh Copson
12 Nov 2025
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Leigh Copson 12 Nov 2025
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  • Tampa Bay Buccaneers at Buffalo Bills picks for Sunday, November 16
  • Game is taking place at Highmark Stadium
  • Preview, predictions, stats & form
(Getty Images)
    Tampa Bay Buccaneers at Buffalo Bills Preview & Picks
  • Tampa Bay Buccaneers at Buffalo Bills Preview & Picks
  • Head To Head
  • Tampa Bay Buccaneers Form
  • Buffalo Bills Form

Tampa Bay Buccaneers at Buffalo Bills Preview & Picks

Tampa Bay are tipped to cover as a betting underdog in Buffalo.

The Buccaneers have covered consistently on the road this season, while the Bills have had some letdowns and have struggled to cover the spread on their home turf.

  • Tampa Bay Buccaneers are 4-1-0 ATS in their 5 road games
  • Buffalo Bills are 2-3-0 ATS in their 5 home games this season
  • The Under has cashed in 4 of Tampa Bay’s 5 road games
  • The Under has hit in 4 of Buffalo’s previous 5 games

Head To Head

  • Tampa Bay Buccaneers lead the all-time series 8-5
  • Buffalo Bills won 24-18 when the two teams last met in October 2023

Tampa Bay Buccaneers Form

Tampa Bay head to Buffalo having lost two of their previous three games to fall to 6-3.

The Buccaneers opened the season with back-to-back wins on the road, beating Atlanta 23-20 and Houston 20-19 to make a flying start.

They made it three-in-a-row with a 29-27 win over the New York Jets, and then bounced back from a 31-25 loss at home to Philadelphia with wins over Seattle, 38-35, and San Francisco, 30-19.

Tampa Bay failed to make it three-in-a-row as they lost 24-9 in Detroit, only to respond with a 23-3 victory in New Orleans.

The Buccaneers failed to follow that up at home though, as they were beaten 28-23 at home by New England.

Buffalo Bills Form

Buffalo return home on the back of a surprise defeat in Miami that dropped their record to 6-3.

The Bills staged a dramatic late fightback to beat Baltimore 41-40 on opening night, and that proved to be the start of a four-game streak to start the season.

They beat the New York Jets 30-10 on the road, before returning back home to down Miami 31-21 and New Orleans 31-19.

Buffalo’s perfect start was ended by a shock 23-20 home defeat to New England, and that was followed by a 24-14 defeat when they visited Atlanta.

The Bills rallied on the road with a 40-9 blowout of Carolina, and then returned home to down Kansas City 28-21, but they failed to make it three-in-a-row as they were beaten 30-13 in Miami last weekend.

Verdict

Buffalo’s defeat in Miami is unlikely to be the start of a major collapse, but we cannot ignore their difficulties in covering the spread this season.

We can also not overlook just how reliable Tampa have been as a spread bet on their travels, so we are taking Baker, the Bucs and the free points.

Best Bet1: Tampa Bay +5.5 Spread @-111.11 at Stake.us - 4 Units
Best Bet2: Under 49.5 Total Points @-111.11 at Stake.us - 2 Units
Tampa Bay +5.5
Spread
@-111.11 - 4 Units
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Under 49.5
Total Points
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