LSU at Clemson Preview & Picks – Clemson To Win Blockbuster College Football Clash
16 Jul 2025
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Louisville vs USC Preview & Picks – Louisville To Beat Caleb Williams-less USC In Holiday Bowl
- Louisville vs USC picks for Wednesday, December 27
- Holiday Bowl kicks-off at 20:00 ET at Petco Park in San Diego
- Preview, predictions, stats & form
- Louisville vs USC Preview & Picks
- Head To Head
- Louisville Form
- USC Form
Louisville vs USC Preview & Picks
Louisville vs USC Preview & Picks
Louisville are tipped to cover the spread as they win the Holiday Bowl.
The Trojans defense gave up a ton of points this season, and for this game they will not have Caleb Williams to counter that.
- Louisville are 4-1-0 ATS in their last 5 games
- USC are 1-5 in their last 6 games
- USC are 1-8-0 ATS in their last 9 games
- The Over has cashed in 3 of Louisville’s last 4 games
Head To Head
- This is the first ever meeting between the two teams
Louisville Form
Louisville enter the Holiday Bowl having lost their last two games, including the ACC Championship.
The Cardinals opened the season with a six-game win streak that culminated with a shock 33-20 win at home to #10 Notre Dame.
They were brought back down to Earth a week later by a 38-21 defeat at Pitt, but when they returned to action they downed #20 Duke 23-0, sparking a four-game win streak.
Louisville blew out Virginia Tech 34-3 and beat Virginia 31-24 at home, before heading to Miami to fend off the Hurricanes in a 38-31 win.
The Cardinals’ streak was halted by a 38-31 loss to Kentucky, and that was followed by a 16-6 loss to Florida State in the conference championship.
USC Form
USC come into this matchup having endured a rough end to the regular season, losing five of their final six games.
The Trojans won their first six games of the season as Caleb Williams and the offense hung at least 42 points on each of those opponents.
However, their momentum stalled as Williams threw a bunch of picks in a 48-20 blowout defeat at #21 Notre Dame.
USC then lost 34-42 to #14 Utah, before finally notching their seventh win of the season, edging California 50-49.
The Trojans were unable to back that up though, losing 52-42 to #5 Washington, 36-27 to #6 Oregon and 38-20 to UCLA to close out the regular season.
Verdict
USC have been in terrible form and now they go into this without star quarterback Caleb Williams.
The defense has been terrible all season, so we are backing Louisville to take advantage and cover the spread.
The defense has been terrible all season, so we are backing Louisville to take advantage and cover the spread.
Louisville -7.5
Spread
@-111.11 - 4 Units
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Over 58.0
Total Points
@-111.11 - 2 Units
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Use promo code NEWBONUS
Sign up with the code NEWBONUS. When you verify your account get 25 Stake Cash for free PLUS 250,000 Gold Coins and 5% Rakeback! No deposit required. Login each day for the next 30 days and get an additional 30 Stake Cash AND 300,000 Gold Coins. 21+ only. T&Cs apply. Excludes WA, NY, NV, ID, KY, MI, VT, NJ, DE, WV, PA, RI & MD.
See also
- Kansas vs UNLV Preview & Picks – Kansas To Enjoy Guaranteed Rate Bowl Success
- North Carolina vs West Virginia Preview & Picks – No Mayo Bowl Win For Drake Maye-less North Carolina
- James Madison vs Air Force Preview & Picks – James Madison To Win Armed Forces Bowl
- UTSA vs Marshall Preview & Picks – UTSA To Cover As Double Digit Frisco Bowl Favorite
- Georgia Tech vs UCF Preview & Picks – Underdogs Georgia Tech To Earn Gasparilla Bowl Cover
- California vs Texas Tech Preview & Picks – Texas Tech To Win Independence Bowl Clash
- Liberty vs Oregon Preview & Picks – Oregon To Crush Liberty In Fiesta Bowl
- Wisconsin vs LSU Preview & Picks – LSU To Cover In ReliaQuest Bowl Victory
- Ole Miss vs Penn State Preview & Picks – Nittany Lions To Claim Peach Bowl Victory
- SMU vs Boston College Preview & Picks – Mustangs To Blow Out ‘Home Team’ In Fenway Bowl
- Texas A&M vs Oklahoma State Preview & Picks – Cowboys To Cover As Texas Bowl Underdog
- Iowa vs Tennessee Preview & Picks – Tennessee To Record Citrus Bowl Cover
- NC State vs Kansas State Preview & Picks – No Pop-Tarts Bowl Cover For Kansas State
- Arizona vs Oklahoma Preview & Picks – Arizona To Win & Cover In Alamo Bowl
- Clemson vs Kentucky Preview & Picks – Gator Bowl Success For Clemson
- Oregon State vs Notre Dame Preview & Picks – Fighting Irish To Ease To Sun Bowl Victory
- Missouri vs Ohio State Preview & Picks – Ohio State To Win College Football’s Cotton Bowl Classic
- Georgia vs Florida State Preview & Picks – FSU To Cover As Double Digit Orange Bowl Underdog
- Michigan vs Alabama Preview & Picks – Underdogs Alabama To Cover College Football Rose Bowl Spread
- Washington vs Texas Preview & Picks – Texas To Cover In College Football Sugar Bowl Win
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